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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR70 All Species: 29.09
Human Site: S418 Identified Species: 42.67
UniProt: Q9NW82 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NW82 NP_060504.1 654 73201 S418 N K P L F S A S G L P T M F P
Chimpanzee Pan troglodytes XP_517797 733 81613 S497 N K P L F S A S G L P T M F P
Rhesus Macaque Macaca mulatta XP_001094466 730 81405 S494 N K P L F S A S G L P T M F P
Dog Lupus familis XP_546343 767 84520 S531 N K P L F S A S G L P T M F P
Cat Felis silvestris
Mouse Mus musculus Q3TWF6 657 73100 S421 N K P L F S A S D L P T L F P
Rat Rattus norvegicus Q5EB92 655 72817 S419 N K P L F S A S D L P T L F P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512414 423 47462 P202 M T D C C F S P D D K L L V T
Chicken Gallus gallus NP_001026621 387 42207 E166 K K I P D S H E I T L Q H G T
Frog Xenopus laevis Q6GPP0 622 68798 S386 K N P L N V A S G L E N F F P
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1J3 655 73589 T419 K Q P L H T W T N L F S R Y D
Honey Bee Apis mellifera XP_393688 664 74562 K432 K T P I F E A K N L Y S R Y D
Nematode Worm Caenorhab. elegans O16519 620 69027 T365 K E P L L V K T G L E N A F K
Sea Urchin Strong. purpuratus XP_794637 641 71917 Q386 L V R P T F H Q K M A H G K G
Poplar Tree Populus trichocarpa XP_002320613 647 71276 E416 K E A L K V F E N L P N N Y A
Maize Zea mays NP_001147117 622 68359 E391 K T P L K V F E D L P N H Y A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_179623 648 71183 E413 K E A L K V F E G L P N Y Y P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.8 88.2 81.2 N.A. 91 92.6 N.A. 55.2 40.5 74.4 N.A. N.A. 42.1 45.4 36.8 45.2
Protein Similarity: 100 88.9 89.1 83.4 N.A. 95.1 96.6 N.A. 59.7 48.4 84.2 N.A. N.A. 63 64.3 55.6 63.9
P-Site Identity: 100 100 100 100 N.A. 86.6 86.6 N.A. 0 13.3 53.3 N.A. N.A. 20 26.6 33.3 0
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 13.3 13.3 53.3 N.A. N.A. 53.3 46.6 46.6 6.6
Percent
Protein Identity: 35.9 38.8 N.A. 37.3 N.A. N.A.
Protein Similarity: 53.2 57.3 N.A. 57.9 N.A. N.A.
P-Site Identity: 20 26.6 N.A. 33.3 N.A. N.A.
P-Site Similarity: 33.3 33.3 N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 0 0 0 50 0 0 0 7 0 7 0 13 % A
% Cys: 0 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 7 0 0 0 25 7 0 0 0 0 13 % D
% Glu: 0 19 0 0 0 7 0 25 0 0 13 0 0 0 0 % E
% Phe: 0 0 0 0 44 13 19 0 0 0 7 0 7 50 0 % F
% Gly: 0 0 0 0 0 0 0 0 44 0 0 0 7 7 7 % G
% His: 0 0 0 0 7 0 13 0 0 0 0 7 13 0 0 % H
% Ile: 0 0 7 7 0 0 0 0 7 0 0 0 0 0 0 % I
% Lys: 50 44 0 0 19 0 7 7 7 0 7 0 0 7 7 % K
% Leu: 7 0 0 75 7 0 0 0 0 82 7 7 19 0 0 % L
% Met: 7 0 0 0 0 0 0 0 0 7 0 0 25 0 0 % M
% Asn: 38 7 0 0 7 0 0 0 19 0 0 32 7 0 0 % N
% Pro: 0 0 69 13 0 0 0 7 0 0 57 0 0 0 50 % P
% Gln: 0 7 0 0 0 0 0 7 0 0 0 7 0 0 0 % Q
% Arg: 0 0 7 0 0 0 0 0 0 0 0 0 13 0 0 % R
% Ser: 0 0 0 0 0 44 7 44 0 0 0 13 0 0 0 % S
% Thr: 0 19 0 0 7 7 0 13 0 7 0 38 0 0 13 % T
% Val: 0 7 0 0 0 32 0 0 0 0 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 7 0 7 32 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _