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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR70
All Species:
30.91
Human Site:
T177
Identified Species:
45.33
UniProt:
Q9NW82
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NW82
NP_060504.1
654
73201
T177
I
P
D
S
H
E
I
T
L
K
H
G
T
K
T
Chimpanzee
Pan troglodytes
XP_517797
733
81613
T256
I
P
D
S
H
E
I
T
L
K
H
G
T
K
T
Rhesus Macaque
Macaca mulatta
XP_001094466
730
81405
T253
I
P
D
S
H
E
I
T
L
K
H
G
T
K
T
Dog
Lupus familis
XP_546343
767
84520
T290
I
P
D
S
H
E
I
T
L
K
H
G
T
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q3TWF6
657
73100
T180
I
P
D
S
H
E
I
T
L
R
H
G
T
K
T
Rat
Rattus norvegicus
Q5EB92
655
72817
T178
I
P
D
S
H
E
I
T
L
K
H
G
T
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512414
423
47462
Chicken
Gallus gallus
NP_001026621
387
42207
Frog
Xenopus laevis
Q6GPP0
622
68798
T145
I
P
D
S
H
E
I
T
L
Q
H
G
T
K
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1J3
655
73589
Q177
I
P
Y
T
H
E
V
Q
M
Q
H
G
S
R
A
Honey Bee
Apis mellifera
XP_393688
664
74562
T190
I
P
C
S
H
E
V
T
M
T
H
G
T
K
A
Nematode Worm
Caenorhab. elegans
O16519
620
69027
L129
G
T
Q
A
I
S
A
L
R
V
E
P
P
G
V
Sea Urchin
Strong. purpuratus
XP_794637
641
71917
D136
R
Q
D
D
D
D
D
D
D
D
M
I
G
P
P
Poplar Tree
Populus trichocarpa
XP_002320613
647
71276
V175
I
P
T
S
N
E
I
V
L
G
G
H
S
K
V
Maize
Zea mays
NP_001147117
622
68359
V150
I
P
L
S
N
E
I
V
L
R
G
H
N
K
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_179623
648
71183
Q172
I
P
L
S
N
E
I
Q
L
K
G
H
T
K
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.8
88.2
81.2
N.A.
91
92.6
N.A.
55.2
40.5
74.4
N.A.
N.A.
42.1
45.4
36.8
45.2
Protein Similarity:
100
88.9
89.1
83.4
N.A.
95.1
96.6
N.A.
59.7
48.4
84.2
N.A.
N.A.
63
64.3
55.6
63.9
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
0
0
93.3
N.A.
N.A.
40
66.6
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
0
100
N.A.
N.A.
80
80
6.6
13.3
Percent
Protein Identity:
35.9
38.8
N.A.
37.3
N.A.
N.A.
Protein Similarity:
53.2
57.3
N.A.
57.9
N.A.
N.A.
P-Site Identity:
46.6
46.6
N.A.
60
N.A.
N.A.
P-Site Similarity:
60
60
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
7
0
0
0
0
0
0
0
13
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
50
7
7
7
7
7
7
7
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
75
0
0
0
0
7
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
0
0
0
0
0
7
19
57
7
7
0
% G
% His:
0
0
0
0
57
0
0
0
0
0
57
19
0
0
0
% H
% Ile:
75
0
0
0
7
0
63
0
0
0
0
7
0
0
7
% I
% Lys:
0
0
0
0
0
0
0
0
0
38
0
0
0
69
0
% K
% Leu:
0
0
13
0
0
0
0
7
63
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
13
0
7
0
0
0
0
% M
% Asn:
0
0
0
0
19
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
75
0
0
0
0
0
0
0
0
0
7
7
7
7
% P
% Gln:
0
7
7
0
0
0
0
13
0
13
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
0
0
0
7
13
0
0
0
7
0
% R
% Ser:
0
0
0
69
0
7
0
0
0
0
0
0
13
0
0
% S
% Thr:
0
7
7
7
0
0
0
50
0
7
0
0
57
0
44
% T
% Val:
0
0
0
0
0
0
13
13
0
7
0
0
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _