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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM51 All Species: 26.06
Human Site: S127 Identified Species: 63.7
UniProt: Q9NW97 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NW97 NP_001129688.1 253 27759 S127 E E D E E A A S R Y Y V P S Y
Chimpanzee Pan troglodytes XP_001148634 212 23357 E94 K R K Q R Q G E D L A H V Q H
Rhesus Macaque Macaca mulatta XP_001082343 251 27509 S125 E E E E E A A S R Y Y V P S Y
Dog Lupus familis XP_848976 250 27565 S124 E E E E E A S S R Y Y V P S Y
Cat Felis silvestris
Mouse Mus musculus Q99LG1 249 27380 S123 E E E E D V S S R Y Y V P S Y
Rat Rattus norvegicus NP_001102743 249 27290 S123 E E E E E A S S R Y Y V P S Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520545 247 27452 S121 S Q E E E S P S R Y Y V P S Y
Chicken Gallus gallus XP_001234352 250 27303 S123 E E D E D V S S R Y Y V P S Y
Frog Xenopus laevis NP_001084526 233 25635 A114 E S S E L D V A R Y S A P S Y
Zebra Danio Brachydanio rerio NP_001096087 225 24340 Q107 E E A V T G G Q Y P I R Q S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.7 98 88.9 N.A. 84.9 86.5 N.A. 77.8 64.8 51.3 36.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 83.7 99.2 92.8 N.A. 89.7 90.5 N.A. 87.3 77 63.2 52.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 93.3 86.6 N.A. 73.3 86.6 N.A. 66.6 80 46.6 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 100 100 N.A. 93.3 100 N.A. 86.6 93.3 53.3 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 40 20 10 0 0 10 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 20 0 20 10 0 0 10 0 0 0 0 0 0 % D
% Glu: 80 70 50 80 50 0 0 10 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 20 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 10 0 0 10 0 0 80 0 0 % P
% Gln: 0 10 0 10 0 10 0 10 0 0 0 0 10 10 0 % Q
% Arg: 0 10 0 0 10 0 0 0 80 0 0 10 0 0 0 % R
% Ser: 10 10 10 0 0 10 40 70 0 0 10 0 0 90 0 % S
% Thr: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 10 0 20 10 0 0 0 0 70 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 80 70 0 0 0 80 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _