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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED9
All Species:
19.09
Human Site:
Y135
Identified Species:
52.5
UniProt:
Q9NWA0
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWA0
NP_060489.1
146
16403
Y135
K
N
E
L
L
Q
K
Y
K
S
L
C
M
F
E
Chimpanzee
Pan troglodytes
XP_001159948
147
16497
Y136
K
N
E
L
L
Q
K
Y
K
S
L
C
M
F
E
Rhesus Macaque
Macaca mulatta
XP_001090318
146
16343
Y135
K
N
E
L
L
Q
K
Y
K
S
L
C
M
F
E
Dog
Lupus familis
XP_851901
147
16303
Y136
K
N
E
L
L
Q
K
Y
K
S
L
C
M
F
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCS6
142
15691
Y131
K
N
E
L
L
Q
K
Y
K
S
L
C
M
F
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4V7L5
115
13464
S106
E
L
L
Q
K
Y
K
S
L
C
M
F
E
I
P
Zebra Danio
Brachydanio rerio
XP_002667479
98
11125
L89
L
L
Q
K
Y
K
S
L
C
M
F
D
I
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZB42
144
16790
Q133
R
N
Q
L
K
L
K
Q
Q
L
I
R
K
Y
K
Honey Bee
Apis mellifera
XP_624543
115
13648
N106
E
L
L
L
K
Y
R
N
M
C
T
F
E
V
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.9
86.3
N.A.
78
N.A.
N.A.
N.A.
N.A.
52.7
46.5
N.A.
29.4
26.7
N.A.
N.A.
Protein Similarity:
100
99.3
99.3
92.5
N.A.
86.3
N.A.
N.A.
N.A.
N.A.
67.1
60.2
N.A.
51.3
52
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
6.6
0
N.A.
20
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
20
26.6
N.A.
60
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
23
0
56
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% D
% Glu:
23
0
56
0
0
0
0
0
0
0
0
0
23
0
56
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
12
23
0
56
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
12
0
12
12
0
% I
% Lys:
56
0
0
12
34
12
78
0
56
0
0
0
12
0
23
% K
% Leu:
12
34
23
78
56
12
0
12
12
12
56
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
12
12
12
0
56
0
0
% M
% Asn:
0
67
0
0
0
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
23
% P
% Gln:
0
0
23
12
0
56
0
12
12
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
0
12
0
0
0
0
12
0
0
0
% R
% Ser:
0
0
0
0
0
0
12
12
0
56
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
23
0
56
0
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _