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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IFT57 All Species: 17.88
Human Site: S64 Identified Species: 30.26
UniProt: Q9NWB7 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NWB7 NP_060480.1 429 49108 S64 E E E F L R K S N L K A P S R
Chimpanzee Pan troglodytes XP_526260 429 49046 S64 E E E F L R K S N L K A P S R
Rhesus Macaque Macaca mulatta XP_001101043 429 48998 S64 E E E F L R K S N L K A P S R
Dog Lupus familis XP_535730 570 64477 H205 E E D L L R K H N L K P P S R
Cat Felis silvestris
Mouse Mus musculus Q8BXG3 429 48753 S64 E E E L L R K S N L K P P S R
Rat Rattus norvegicus NP_001100563 429 48762 S64 E E E L L R K S N L K P P S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518621 415 47398 A61 P P S R H Y F A L P T N P G E
Chicken Gallus gallus XP_416624 532 60520 H167 E E E A L R R H N V R P L S R
Frog Xenopus laevis A9ULY7 411 47255 L57 L S R H Y F A L P T N P G E Q
Zebra Danio Brachydanio rerio Q6IVW0 407 46575 P53 R H Y F V S S P H V L S N P G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQS5 405 47155 A51 S R F Y F V K A T N P G E Q F
Honey Bee Apis mellifera XP_625220 407 47200 R53 F K I K A I N R N Y F V T Q T
Nematode Worm Caenorhab. elegans Q93833 412 46486 V58 G F L K L G V V Y K P I L K H
Sea Urchin Strong. purpuratus XP_001192285 405 46654 S51 E L G F K P L S R H Y F A I A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.8 69.3 N.A. 90.6 90.9 N.A. 79.7 61 73.4 62 N.A. 34.2 46.8 37 58.9
Protein Similarity: 100 99.7 99.5 72.2 N.A. 93.9 94.1 N.A. 86.7 71.9 84.3 77.8 N.A. 55.2 66.6 62.7 75.9
P-Site Identity: 100 100 100 73.3 N.A. 86.6 86.6 N.A. 6.6 53.3 0 6.6 N.A. 6.6 6.6 6.6 20
P-Site Similarity: 100 100 100 80 N.A. 86.6 86.6 N.A. 13.3 73.3 6.6 33.3 N.A. 20 13.3 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 8 15 0 0 0 22 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 58 50 43 0 0 0 0 0 0 0 0 0 8 8 8 % E
% Phe: 8 8 8 36 8 8 8 0 0 0 8 8 0 0 8 % F
% Gly: 8 0 8 0 0 8 0 0 0 0 0 8 8 8 8 % G
% His: 0 8 0 8 8 0 0 15 8 8 0 0 0 0 8 % H
% Ile: 0 0 8 0 0 8 0 0 0 0 0 8 0 8 0 % I
% Lys: 0 8 0 15 8 0 50 0 0 8 43 0 0 8 0 % K
% Leu: 8 8 8 22 58 0 8 8 8 43 8 0 15 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 58 8 8 8 8 0 0 % N
% Pro: 8 8 0 0 0 8 0 8 8 8 15 36 50 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 8 % Q
% Arg: 8 8 8 8 0 50 8 8 8 0 8 0 0 0 50 % R
% Ser: 8 8 8 0 0 8 8 43 0 0 0 8 0 50 0 % S
% Thr: 0 0 0 0 0 0 0 0 8 8 8 0 8 0 8 % T
% Val: 0 0 0 0 8 8 8 8 0 15 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 8 8 8 0 0 8 8 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _