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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM45A
All Species:
23.18
Human Site:
S271
Identified Species:
51
UniProt:
Q9NWC5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWC5
NP_060474.1
275
31680
S271
N
A
E
R
E
Q
E
S
E
E
E
M
_
_
_
Chimpanzee
Pan troglodytes
XP_516625
310
35385
P287
S
I
Q
G
N
A
L
P
H
V
S
S
P
P
E
Rhesus Macaque
Macaca mulatta
XP_001093702
275
31596
S271
N
A
E
R
E
Q
E
S
E
E
E
M
_
_
_
Dog
Lupus familis
XP_535720
275
31594
S271
N
A
E
R
E
Q
E
S
E
E
E
M
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q60774
273
31324
S269
H
A
D
R
E
Q
E
S
E
E
E
V
_
_
_
Rat
Rattus norvegicus
Q497B2
278
32319
Q268
L
K
S
D
H
T
Y
Q
S
T
L
L
S
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514618
275
31990
S271
T
A
E
R
D
Q
E
S
E
E
E
M
_
_
_
Chicken
Gallus gallus
XP_416606
275
31774
S271
T
S
E
R
D
Q
E
S
E
D
E
I
_
_
_
Frog
Xenopus laevis
Q6NS09
280
31983
V269
I
N
S
K
K
A
E
V
E
A
S
L
L
A
G
Zebra Danio
Brachydanio rerio
Q6P0S3
283
32742
S271
K
S
T
S
T
D
S
S
S
Q
K
A
L
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783137
274
30760
A269
R
Y
E
L
A
E
T
A
Q
S
L
D
S
_
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.2
94.9
77.8
N.A.
64.3
43.1
N.A.
64.3
54.1
43.9
45.5
N.A.
N.A.
N.A.
N.A.
32.7
Protein Similarity:
100
84.1
98.1
88
N.A.
80.7
64.3
N.A.
78.9
74.5
65
62.5
N.A.
N.A.
N.A.
N.A.
49.4
P-Site Identity:
100
0
100
100
N.A.
75
0
N.A.
83.3
58.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
7.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
13.3
N.A.
91.6
91.6
40
26.6
N.A.
N.A.
N.A.
N.A.
30.7
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
46
0
0
10
19
0
10
0
10
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
19
10
0
0
0
10
0
10
0
0
0
% D
% Glu:
0
0
55
0
37
10
64
0
64
46
55
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
10
% G
% His:
10
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
10
10
0
10
10
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
10
0
0
10
0
0
10
0
0
0
19
19
19
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
37
0
0
0
% M
% Asn:
28
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
10
10
0
% P
% Gln:
0
0
10
0
0
55
0
10
10
10
0
0
0
0
10
% Q
% Arg:
10
0
0
55
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
19
19
10
0
0
10
64
19
10
19
10
19
0
10
% S
% Thr:
19
0
10
0
10
10
10
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
55
64
64
% _