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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM45A
All Species:
22.42
Human Site:
Y39
Identified Species:
49.33
UniProt:
Q9NWC5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWC5
NP_060474.1
275
31680
Y39
K
K
Q
K
R
T
C
Y
L
G
S
K
T
L
F
Chimpanzee
Pan troglodytes
XP_516625
310
35385
Y55
K
K
Q
K
R
T
C
Y
L
G
S
K
T
L
F
Rhesus Macaque
Macaca mulatta
XP_001093702
275
31596
Y39
K
K
Q
K
R
T
C
Y
L
G
S
K
T
L
F
Dog
Lupus familis
XP_535720
275
31594
Y39
K
K
H
K
R
T
S
Y
L
G
S
K
A
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q60774
273
31324
Y39
K
R
Q
T
R
T
C
Y
L
N
S
K
T
L
L
Rat
Rattus norvegicus
Q497B2
278
32319
K37
F
H
Q
K
G
L
K
K
N
R
L
S
L
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514618
275
31990
Y39
K
K
N
K
R
A
C
Y
L
G
S
K
A
G
L
Chicken
Gallus gallus
XP_416606
275
31774
Y39
R
K
N
K
S
A
C
Y
L
G
S
R
A
G
F
Frog
Xenopus laevis
Q6NS09
280
31983
R39
S
K
V
K
G
N
C
R
S
N
K
C
Y
D
R
Zebra Danio
Brachydanio rerio
Q6P0S3
283
32742
G39
R
R
K
E
R
Q
V
G
D
R
E
R
Q
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783137
274
30760
P39
L
D
N
G
R
Q
R
P
R
S
R
V
M
Y
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.2
94.9
77.8
N.A.
64.3
43.1
N.A.
64.3
54.1
43.9
45.5
N.A.
N.A.
N.A.
N.A.
32.7
Protein Similarity:
100
84.1
98.1
88
N.A.
80.7
64.3
N.A.
78.9
74.5
65
62.5
N.A.
N.A.
N.A.
N.A.
49.4
P-Site Identity:
100
100
100
80
N.A.
73.3
13.3
N.A.
66.6
53.3
20
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
80
13.3
N.A.
66.6
66.6
20
40
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
19
0
0
0
0
0
0
28
0
0
% A
% Cys:
0
0
0
0
0
0
64
0
0
0
0
10
0
0
10
% C
% Asp:
0
10
0
0
0
0
0
0
10
0
0
0
0
10
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
46
% F
% Gly:
0
0
0
10
19
0
0
10
0
55
0
0
0
19
0
% G
% His:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
55
64
10
73
0
0
10
10
0
0
10
55
0
10
0
% K
% Leu:
10
0
0
0
0
10
0
0
64
0
10
0
10
46
28
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
28
0
0
10
0
0
10
19
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
46
0
0
19
0
0
0
0
0
0
10
10
10
% Q
% Arg:
19
19
0
0
73
0
10
10
10
19
10
19
0
0
10
% R
% Ser:
10
0
0
0
10
0
10
0
10
10
64
10
0
0
0
% S
% Thr:
0
0
0
10
0
46
0
0
0
0
0
0
37
0
0
% T
% Val:
0
0
10
0
0
0
10
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
64
0
0
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _