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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM45A
All Species:
20.3
Human Site:
Y80
Identified Species:
44.67
UniProt:
Q9NWC5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWC5
NP_060474.1
275
31680
Y80
G
G
P
H
L
M
L
Y
D
Y
K
Q
G
H
W
Chimpanzee
Pan troglodytes
XP_516625
310
35385
Y96
G
G
P
H
L
M
L
Y
D
Y
K
Q
G
H
W
Rhesus Macaque
Macaca mulatta
XP_001093702
275
31596
Y80
G
G
P
N
L
M
L
Y
D
Y
K
Q
G
H
W
Dog
Lupus familis
XP_535720
275
31594
Y80
G
G
P
H
L
A
L
Y
N
Y
K
E
G
Q
W
Cat
Felis silvestris
Mouse
Mus musculus
Q60774
273
31324
I78
I
S
G
G
P
A
L
I
L
H
K
D
G
Q
W
Rat
Rattus norvegicus
Q497B2
278
32319
L77
P
D
G
P
H
L
H
L
Y
H
E
N
Q
W
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514618
275
31990
Y80
D
G
P
H
M
N
L
Y
N
Y
E
E
K
H
W
Chicken
Gallus gallus
XP_416606
275
31774
Y80
D
G
P
H
L
K
L
Y
N
Y
E
E
K
H
W
Frog
Xenopus laevis
Q6NS09
280
31983
V78
D
G
P
H
M
H
L
V
N
G
E
D
H
S
W
Zebra Danio
Brachydanio rerio
Q6P0S3
283
32742
A81
F
V
P
D
G
P
H
A
H
L
Y
Q
D
G
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783137
274
30760
L78
Y
S
E
P
V
L
V
L
V
D
K
D
G
H
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.2
94.9
77.8
N.A.
64.3
43.1
N.A.
64.3
54.1
43.9
45.5
N.A.
N.A.
N.A.
N.A.
32.7
Protein Similarity:
100
84.1
98.1
88
N.A.
80.7
64.3
N.A.
78.9
74.5
65
62.5
N.A.
N.A.
N.A.
N.A.
49.4
P-Site Identity:
100
100
93.3
73.3
N.A.
26.6
0
N.A.
53.3
60
33.3
20
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
86.6
N.A.
33.3
20
N.A.
80
80
53.3
20
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
19
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
28
10
0
10
0
0
0
0
28
10
0
28
10
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
37
28
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
37
64
19
10
10
0
0
0
0
10
0
0
55
10
0
% G
% His:
0
0
0
55
10
10
19
0
10
19
0
0
10
55
0
% H
% Ile:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
0
55
0
19
0
0
% K
% Leu:
0
0
0
0
46
19
73
19
10
10
0
0
0
0
0
% L
% Met:
0
0
0
0
19
28
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
10
0
0
37
0
0
10
0
0
0
% N
% Pro:
10
0
73
19
10
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
37
10
19
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
19
0
0
0
0
0
0
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
10
0
0
10
0
10
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
91
% W
% Tyr:
10
0
0
0
0
0
0
55
10
55
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _