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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPR172B All Species: 27.88
Human Site: Y433 Identified Species: 61.33
UniProt: Q9NWF4 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NWF4 NP_001098047.1 448 46345 Y433 M F P P T S I Y H V F Q S R K
Chimpanzee Pan troglodytes XP_523560 448 46342 Y433 M F P P T S I Y H V F Q S R K
Rhesus Macaque Macaca mulatta XP_001099620 448 46265 Y433 M F P P T S I Y H V F Q S R K
Dog Lupus familis XP_532355 447 46290 Y432 M F P P T S I Y H V F R S G K
Cat Felis silvestris
Mouse Mus musculus Q9D8F3 450 46846 Y435 M F P P T S I Y R V F R S G K
Rat Rattus norvegicus NP_001103140 450 46937 Y435 M F P P T S V Y P V F R S G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518778 436 45509 F423 M F P L V N V F G Y F R Q A D
Chicken Gallus gallus XP_417443 388 42327 H376 S P C P L L Q H S Q W G D A I
Frog Xenopus laevis NP_001088340 438 47632 Y423 M F P M V S I Y H L F Q S G R
Zebra Danio Brachydanio rerio NP_955950 418 45457 Y404 M F P M V S V Y Q V F Q R A R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798899 657 72730 L446 I F P F V N V L S V F V P Y Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.6 85.7 N.A. 80.4 80.2 N.A. 42.6 29.2 52 47 N.A. N.A. N.A. N.A. 24.3
Protein Similarity: 100 99.7 98.4 91.2 N.A. 87.5 87.7 N.A. 56.4 44.8 66.7 63.1 N.A. N.A. N.A. N.A. 37.4
P-Site Identity: 100 100 100 86.6 N.A. 80 66.6 N.A. 26.6 6.6 66.6 53.3 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 53.3 20 80 66.6 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 28 0 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % E
% Phe: 0 91 0 10 0 0 0 10 0 0 91 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 0 0 10 0 37 0 % G
% His: 0 0 0 0 0 0 0 10 46 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 55 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 46 % K
% Leu: 0 0 0 10 10 10 0 10 0 10 0 0 0 0 0 % L
% Met: 82 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 91 64 0 0 0 0 10 0 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 10 10 0 46 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 10 0 0 37 10 28 19 % R
% Ser: 10 0 0 0 0 73 0 0 19 0 0 0 64 0 0 % S
% Thr: 0 0 0 0 55 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 37 0 37 0 0 73 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 73 0 10 0 0 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _