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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF216
All Species:
16.67
Human Site:
T189
Identified Species:
45.83
UniProt:
Q9NWF9
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWF9
NP_996994.1
866
99406
T189
N
Q
Q
P
R
E
I
T
N
Q
V
V
P
Q
E
Chimpanzee
Pan troglodytes
XP_001140528
866
99406
T189
N
Q
Q
P
R
E
I
T
N
Q
V
V
P
Q
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536887
927
106214
T245
N
Q
Q
S
R
E
I
T
N
Q
V
V
P
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
P58283
853
97664
T178
N
P
Q
P
Q
E
R
T
N
Q
V
V
P
Q
E
Rat
Rattus norvegicus
NP_001100592
910
104126
T235
N
P
Q
P
Q
E
R
T
N
Q
L
V
P
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512418
872
99127
A193
D
R
E
P
Q
V
F
A
N
P
L
V
P
L
Q
Chicken
Gallus gallus
XP_414793
928
104312
L250
D
E
E
P
R
A
V
L
N
G
C
V
P
Q
Q
Frog
Xenopus laevis
NP_001108292
865
98344
N197
L
Q
E
G
L
S
R
N
C
H
A
S
L
Q
K
Zebra Danio
Brachydanio rerio
XP_687871
929
104820
R239
S
R
E
H
A
L
R
R
P
P
L
R
D
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
87.6
N.A.
87
82.3
N.A.
76.2
67.5
57.2
42.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
N.A.
89.9
N.A.
91.6
88.2
N.A.
85.5
77.6
72.1
58.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
80
73.3
N.A.
26.6
40
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
86.6
86.6
N.A.
66.6
73.3
26.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
12
0
12
0
0
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
12
0
0
0
0
% C
% Asp:
23
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% D
% Glu:
0
12
45
0
0
56
0
0
0
0
0
0
0
0
56
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
0
0
0
0
12
0
0
0
0
0
% G
% His:
0
0
0
12
0
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
12
% K
% Leu:
12
0
0
0
12
12
0
12
0
0
34
0
12
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
56
0
0
0
0
0
0
12
78
0
0
0
0
0
0
% N
% Pro:
0
23
0
67
0
0
0
0
12
23
0
0
78
0
0
% P
% Gln:
0
45
56
0
34
0
0
0
0
56
0
0
0
78
23
% Q
% Arg:
0
23
0
0
45
0
45
12
0
0
0
12
0
0
0
% R
% Ser:
12
0
0
12
0
12
0
0
0
0
0
12
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
56
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
12
12
0
0
0
45
78
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _