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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF216 All Species: 26.67
Human Site: Y437 Identified Species: 73.33
UniProt: Q9NWF9 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NWF9 NP_996994.1 866 99406 Y437 K Q M N Q Y S Y I D F K F E Q
Chimpanzee Pan troglodytes XP_001140528 866 99406 Y437 K Q M N Q Y S Y I D F K F E Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536887 927 106214 Y498 K E M N Q Y S Y I D F K F E Q
Cat Felis silvestris
Mouse Mus musculus P58283 853 97664 F425 K E M N Q Y S F I D F K F E Q
Rat Rattus norvegicus NP_001100592 910 104126 F482 K E M N Q Y S F I D F K F E Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512418 872 99127 Y443 K E M N Q Y S Y I D F K F E Q
Chicken Gallus gallus XP_414793 928 104312 Y499 K E M N Q Y S Y I D F K F E Q
Frog Xenopus laevis NP_001108292 865 98344 Y440 K E M N Q F S Y I D F K F E Q
Zebra Danio Brachydanio rerio XP_687871 929 104820 Y506 R E P N E R A Y I D F K F E Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 N.A. 87.6 N.A. 87 82.3 N.A. 76.2 67.5 57.2 42.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 N.A. 89.9 N.A. 91.6 88.2 N.A. 85.5 77.6 72.1 58.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 86.6 86.6 N.A. 93.3 93.3 86.6 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 100 86.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % D
% Glu: 0 78 0 0 12 0 0 0 0 0 0 0 0 100 0 % E
% Phe: 0 0 0 0 0 12 0 23 0 0 100 0 100 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % I
% Lys: 89 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 89 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 23 0 0 89 0 0 0 0 0 0 0 0 0 100 % Q
% Arg: 12 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 89 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 78 0 78 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _