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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNHIT6 All Species: 23.64
Human Site: Y417 Identified Species: 65
UniProt: Q9NWK9 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NWK9 NP_060423.2 470 53918 Y417 M Q Q N L V R Y Y E L D P Y K
Chimpanzee Pan troglodytes XP_001142619 470 53888 Y417 M Q Q N L V R Y Y E L D P Y K
Rhesus Macaque Macaca mulatta XP_001109136 470 54124 Y417 M Q Q N L V R Y Y E L D P Y K
Dog Lupus familis XP_537090 468 53741 Y415 M Q Q N L V R Y Y E L D P C K
Cat Felis silvestris
Mouse Mus musculus Q3UFB2 460 52195 Y408 M Q Q N M I R Y H E L D P Y K
Rat Rattus norvegicus NP_001099673 461 52762 Y408 M Q Q N L I R Y Y E L D P S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518032 157 18029 P105 N I D L K I L P V G F T K R R
Chicken Gallus gallus XP_422364 290 32987 K238 L L E N L K N K V I I E Y P T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q56ZI2 683 75990 Y526 V P W W Y I P Y Y K T F G S I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.1 77.8 N.A. 72.5 71.9 N.A. 20.6 38.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 98.3 84.4 N.A. 81.6 81.2 N.A. 27.4 47.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 80 86.6 N.A. 0 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 93.3 N.A. 13.3 40 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35.8 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % C
% Asp: 0 0 12 0 0 0 0 0 0 0 0 67 0 0 0 % D
% Glu: 0 0 12 0 0 0 0 0 0 67 0 12 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 12 12 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 12 0 0 12 0 0 % G
% His: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % H
% Ile: 0 12 0 0 0 45 0 0 0 12 12 0 0 0 12 % I
% Lys: 0 0 0 0 12 12 0 12 0 12 0 0 12 0 67 % K
% Leu: 12 12 0 12 67 0 12 0 0 0 67 0 0 0 0 % L
% Met: 67 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 0 78 0 0 12 0 0 0 0 0 0 0 0 % N
% Pro: 0 12 0 0 0 0 12 12 0 0 0 0 67 12 0 % P
% Gln: 0 67 67 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 67 0 0 0 0 0 0 12 12 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 23 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 12 12 0 0 12 % T
% Val: 12 0 0 0 0 45 0 0 23 0 0 0 0 0 0 % V
% Trp: 0 0 12 12 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 12 0 0 78 67 0 0 0 12 45 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _