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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAG1 All Species: 8.18
Human Site: Y387 Identified Species: 20
UniProt: Q9NWQ8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NWQ8 NP_060910.3 432 46981 Y387 S E E P E P D Y E A I Q T L N
Chimpanzee Pan troglodytes XP_001168080 432 46923 Y387 G E E P E P D Y E A I H T L N
Rhesus Macaque Macaca mulatta XP_001091544 432 47237 Y387 G E E P E P D Y E A I Q T L H
Dog Lupus familis XP_853555 433 47261 P386 R P G E E P E P D Y E A I Q T
Cat Felis silvestris
Mouse Mus musculus Q3U1F9 429 46531 P384 R P S E E P E P D Y E A I Q T
Rat Rattus norvegicus Q9JM80 424 45896 P379 R P G E E P E P D Y E A I Q T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518942 468 49451 L396 D Y A A I Q S L G R D E G R A
Chicken Gallus gallus XP_418306 318 34796 N274 E N E N V Q E N E V D E G E G
Frog Xenopus laevis NP_001086679 438 48151 G393 A T D K A N G G S D P E Y E A
Zebra Danio Brachydanio rerio XP_001339529 405 42569 E361 Q P S E G L T E N A E P G Y E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 96 84.9 N.A. 78.9 79.8 N.A. 56.4 47.6 50.4 38.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99 96.5 89.8 N.A. 85.6 84.4 N.A. 67 58 64.6 53.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 86.6 86.6 13.3 N.A. 13.3 13.3 N.A. 0 13.3 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 86.6 93.3 26.6 N.A. 26.6 26.6 N.A. 6.6 26.6 20 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 10 10 0 0 0 0 40 0 30 0 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 0 0 0 30 0 30 10 20 0 0 0 0 % D
% Glu: 10 30 40 40 60 0 40 10 40 0 40 30 0 20 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 20 0 20 0 10 0 10 10 10 0 0 0 30 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 30 0 30 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 10 0 10 0 0 0 0 0 30 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 10 0 10 0 10 10 0 0 0 0 0 20 % N
% Pro: 0 40 0 30 0 60 0 30 0 0 10 10 0 0 0 % P
% Gln: 10 0 0 0 0 20 0 0 0 0 0 20 0 30 0 % Q
% Arg: 30 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % R
% Ser: 10 0 20 0 0 0 10 0 10 0 0 0 0 0 0 % S
% Thr: 0 10 0 0 0 0 10 0 0 0 0 0 30 0 30 % T
% Val: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 30 0 30 0 0 10 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _