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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC109B All Species: 2.42
Human Site: T11 Identified Species: 5.93
UniProt: Q9NWR8 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NWR8 NP_060388.2 336 39082 T11 R G L W P W R T R L L P T P G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001087164 355 41116 S30 C L K P R E E S E S I V S C I
Dog Lupus familis XP_535692 337 38724 R12 R G A W T R G R R L P A T P G
Cat Felis silvestris
Mouse Mus musculus Q810S1 345 39780 W20 S G L C L G R W Q L L R T I R
Rat Rattus norvegicus XP_001076863 335 39120 L13 L C L G R W R L M P I R T H G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506201 437 50581 G21 Q S L L I F S G T I T G I Y L
Chicken Gallus gallus XP_420651 454 51651 F28 R R R A T A W F R E V P L P G
Frog Xenopus laevis NP_001087837 319 37200 W8 M S V L A G L W R R I P V A A
Zebra Danio Brachydanio rerio Q08BI9 376 42846 S8 M A A K V C R S V L L L S R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787049 316 36823 Q15 R V Q L C Q H Q R G I L L R G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 84.5 81.3 N.A. 71.5 72.3 N.A. 50.1 45.8 51.4 38.2 N.A. N.A. N.A. N.A. 35.4
Protein Similarity: 100 N.A. 86.7 86.9 N.A. 82.3 84.5 N.A. 63.6 59 71.1 60.3 N.A. N.A. N.A. N.A. 58.6
P-Site Identity: 100 N.A. 0 53.3 N.A. 40 33.3 N.A. 6.6 33.3 13.3 20 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 N.A. 20 53.3 N.A. 46.6 40 N.A. 26.6 40 26.6 33.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 20 10 10 10 0 0 0 0 0 10 0 10 10 % A
% Cys: 10 10 0 10 10 10 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 10 10 0 10 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 30 0 10 0 20 10 10 0 10 0 10 0 0 50 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 10 40 0 10 10 10 % I
% Lys: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 10 40 30 10 0 10 10 0 40 30 20 20 0 10 % L
% Met: 20 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 10 0 0 0 0 10 10 30 0 30 0 % P
% Gln: 10 0 10 0 0 10 0 10 10 0 0 0 0 0 0 % Q
% Arg: 40 10 10 0 20 10 40 10 50 10 0 20 0 20 10 % R
% Ser: 10 20 0 0 0 0 10 20 0 10 0 0 20 0 10 % S
% Thr: 0 0 0 0 20 0 0 10 10 0 10 0 40 0 0 % T
% Val: 0 10 10 0 10 0 0 0 10 0 10 10 10 0 0 % V
% Trp: 0 0 0 20 0 20 10 20 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _