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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIH1D1
All Species:
29.09
Human Site:
S181
Identified Species:
58.18
UniProt:
Q9NWS0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWS0
NP_060386.1
290
32363
S181
I
S
Q
Q
N
I
R
S
E
Q
R
P
R
I
Q
Chimpanzee
Pan troglodytes
XP_512819
262
29518
A169
L
G
D
L
Y
T
P
A
P
G
R
A
E
S
G
Rhesus Macaque
Macaca mulatta
XP_001115013
290
32482
S181
I
S
Q
Q
N
I
R
S
Q
Q
R
P
R
I
Q
Dog
Lupus familis
XP_854758
290
32612
S181
I
S
Q
Q
N
I
R
S
Q
Q
R
P
R
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQJ2
290
32190
S181
I
S
Q
Q
N
I
R
S
Q
Q
R
P
R
I
Q
Rat
Rattus norvegicus
Q4V7F5
290
32342
S181
I
S
Q
Q
S
I
R
S
Q
Q
R
P
R
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZWY2
297
33638
T180
I
S
D
Q
N
I
R
T
K
S
K
P
I
I
Q
Zebra Danio
Brachydanio rerio
Q1RM55
287
32011
T179
I
A
E
Q
N
I
R
T
K
S
K
P
I
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609590
335
38003
N193
L
V
T
H
R
V
R
N
E
D
M
K
R
A
Q
Honey Bee
Apis mellifera
XP_001122496
243
27777
E162
V
L
L
K
Q
F
L
E
G
T
S
I
H
L
I
Nematode Worm
Caenorhab. elegans
NP_505775
291
33705
N199
D
D
V
A
E
M
K
N
E
M
F
G
L
K
H
Sea Urchin
Strong. purpuratus
XP_797263
366
40885
T189
L
H
Q
H
H
L
R
T
K
S
K
P
R
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.6
96.9
91
N.A.
80.3
81.7
N.A.
N.A.
N.A.
44.4
39.3
N.A.
25.6
21
25.4
29.7
Protein Similarity:
100
90
98.6
95.8
N.A.
88.9
89.6
N.A.
N.A.
N.A.
64.6
63.4
N.A.
44.4
40.3
49.8
51.9
P-Site Identity:
100
6.6
93.3
93.3
N.A.
93.3
86.6
N.A.
N.A.
N.A.
60
53.3
N.A.
26.6
0
6.6
33.3
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
N.A.
N.A.
80
86.6
N.A.
46.6
20
26.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
0
0
9
0
0
0
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
17
0
0
0
0
0
0
9
0
0
0
0
0
% D
% Glu:
0
0
9
0
9
0
0
9
25
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
9
9
0
9
0
0
9
% G
% His:
0
9
0
17
9
0
0
0
0
0
0
0
9
0
9
% H
% Ile:
59
0
0
0
0
59
0
0
0
0
0
9
17
67
9
% I
% Lys:
0
0
0
9
0
0
9
0
25
0
25
9
0
9
0
% K
% Leu:
25
9
9
9
0
9
9
0
0
0
0
0
9
9
9
% L
% Met:
0
0
0
0
0
9
0
0
0
9
9
0
0
0
0
% M
% Asn:
0
0
0
0
50
0
0
17
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
9
0
0
67
0
0
0
% P
% Gln:
0
0
50
59
9
0
0
0
34
42
0
0
0
0
67
% Q
% Arg:
0
0
0
0
9
0
75
0
0
0
50
0
59
0
0
% R
% Ser:
0
50
0
0
9
0
0
42
0
25
9
0
0
9
0
% S
% Thr:
0
0
9
0
0
9
0
25
0
9
0
0
0
0
0
% T
% Val:
9
9
9
0
0
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _