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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIH1D1
All Species:
20.91
Human Site:
Y258
Identified Species:
41.82
UniProt:
Q9NWS0
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWS0
NP_060386.1
290
32363
Y258
Q
L
Y
H
L
D
A
Y
I
P
L
Q
I
N
S
Chimpanzee
Pan troglodytes
XP_512819
262
29518
Y230
Q
L
Y
H
L
D
A
Y
I
P
L
Q
I
N
S
Rhesus Macaque
Macaca mulatta
XP_001115013
290
32482
Y258
Q
L
Y
H
L
D
A
Y
I
P
L
Q
I
N
S
Dog
Lupus familis
XP_854758
290
32612
Y258
Q
L
Y
H
L
D
A
Y
I
P
L
R
I
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQJ2
290
32190
T258
Q
L
Y
H
L
D
A
T
V
P
L
R
I
N
S
Rat
Rattus norvegicus
Q4V7F5
290
32342
C258
Q
L
Y
H
L
D
A
C
I
P
L
R
I
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZWY2
297
33638
F267
D
L
Y
H
L
D
I
F
L
P
Y
N
I
V
Q
Zebra Danio
Brachydanio rerio
Q1RM55
287
32011
F257
S
L
F
H
L
D
I
F
F
P
V
L
I
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609590
335
38003
F305
Y
G
Y
V
F
N
K
F
V
N
Y
R
L
Q
Q
Honey Bee
Apis mellifera
XP_001122496
243
27777
V219
N
I
E
S
V
K
C
V
L
D
S
N
F
R
V
Nematode Worm
Caenorhab. elegans
NP_505775
291
33705
G262
S
R
S
L
Y
D
F
G
L
P
F
H
I
N
P
Sea Urchin
Strong. purpuratus
XP_797263
366
40885
Y301
K
A
Y
H
L
D
I
Y
L
P
F
D
V
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.6
96.9
91
N.A.
80.3
81.7
N.A.
N.A.
N.A.
44.4
39.3
N.A.
25.6
21
25.4
29.7
Protein Similarity:
100
90
98.6
95.8
N.A.
88.9
89.6
N.A.
N.A.
N.A.
64.6
63.4
N.A.
44.4
40.3
49.8
51.9
P-Site Identity:
100
100
100
93.3
N.A.
80
86.6
N.A.
N.A.
N.A.
46.6
40
N.A.
6.6
0
26.6
40
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
60
66.6
N.A.
40
20
33.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
50
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
84
0
0
0
9
0
9
0
17
0
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
9
0
9
0
9
25
9
0
17
0
9
0
0
% F
% Gly:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
75
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
9
0
0
0
0
25
0
42
0
0
0
75
0
0
% I
% Lys:
9
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
67
0
9
75
0
0
0
34
0
50
9
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
9
0
0
0
9
0
17
0
59
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
84
0
0
0
0
9
% P
% Gln:
50
0
0
0
0
0
0
0
0
0
0
25
0
9
34
% Q
% Arg:
0
9
0
0
0
0
0
0
0
0
0
34
0
9
0
% R
% Ser:
17
0
9
9
0
0
0
0
0
0
9
0
0
0
50
% S
% Thr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% T
% Val:
0
0
0
9
9
0
0
9
17
0
9
0
9
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
75
0
9
0
0
42
0
0
17
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _