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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK1IP1
All Species:
26.67
Human Site:
S208
Identified Species:
45.13
UniProt:
Q9NWT1
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWT1
NP_060376.2
392
43964
S208
I
T
N
E
K
R
I
S
S
V
K
F
L
S
E
Chimpanzee
Pan troglodytes
XP_518863
393
44017
S209
I
T
N
E
K
R
I
S
S
V
K
F
L
S
E
Rhesus Macaque
Macaca mulatta
XP_001087458
392
43967
S208
I
T
N
E
K
R
I
S
S
V
K
F
L
S
E
Dog
Lupus familis
XP_535884
391
43743
S210
I
T
N
E
K
R
I
S
S
V
T
F
L
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCE5
382
42097
S208
I
T
N
G
K
R
I
S
S
V
T
F
L
S
D
Rat
Rattus norvegicus
NP_001032433
382
42216
S208
L
T
N
G
K
R
I
S
A
I
T
F
L
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514604
358
39493
A190
E
K
R
I
S
S
V
A
F
I
S
E
S
V
L
Chicken
Gallus gallus
Q5ZKU8
369
41214
S201
I
T
I
E
K
R
I
S
S
I
R
F
I
T
D
Frog
Xenopus laevis
Q68FJ6
363
40513
A194
V
Y
Q
L
E
T
A
A
V
V
G
T
I
N
N
Zebra Danio
Brachydanio rerio
Q6TNS2
368
40882
S199
V
D
I
Y
T
L
D
S
A
T
I
I
G
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181466
538
58474
L212
Y
K
S
N
V
K
I
L
S
A
C
F
L
T
S
Poplar Tree
Populus trichocarpa
XP_002318775
332
35851
F164
L
V
R
G
R
R
S
F
Y
C
R
L
G
K
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176683
345
37437
V177
L
G
H
E
A
S
L
V
K
F
D
P
S
G
E
Baker's Yeast
Sacchar. cerevisiae
P20484
468
53654
L292
I
V
F
Q
R
K
T
L
M
H
I
E
T
H
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.1
85.4
N.A.
72.4
75.2
N.A.
65
63
60.4
53
N.A.
N.A.
N.A.
N.A.
27.7
Protein Similarity:
100
99.7
97.6
92.8
N.A.
83.9
83.4
N.A.
76.5
78.5
75
69.6
N.A.
N.A.
N.A.
N.A.
44.8
P-Site Identity:
100
100
100
93.3
N.A.
80
60
N.A.
0
60
6.6
6.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
20
93.3
40
26.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
26.2
N.A.
N.A.
27
20.9
N.A.
Protein Similarity:
46.1
N.A.
N.A.
47.9
37.8
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
15
15
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
8
0
0
0
8
0
0
0
22
% D
% Glu:
8
0
0
43
8
0
0
0
0
0
0
15
0
0
43
% E
% Phe:
0
0
8
0
0
0
0
8
8
8
0
58
0
0
0
% F
% Gly:
0
8
0
22
0
0
0
0
0
0
8
0
15
8
0
% G
% His:
0
0
8
0
0
0
0
0
0
8
0
0
0
8
0
% H
% Ile:
50
0
15
8
0
0
58
0
0
22
15
8
15
0
15
% I
% Lys:
0
15
0
0
50
15
0
0
8
0
22
0
0
8
0
% K
% Leu:
22
0
0
8
0
8
8
15
0
0
0
8
50
0
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
43
8
0
0
0
0
0
0
0
0
0
8
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
15
0
15
58
0
0
0
0
15
0
0
0
0
% R
% Ser:
0
0
8
0
8
15
8
58
50
0
8
0
15
43
8
% S
% Thr:
0
50
0
0
8
8
8
0
0
8
22
8
8
22
0
% T
% Val:
15
15
0
0
8
0
8
8
8
43
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
8
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _