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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK1IP1 All Species: 15.76
Human Site: S285 Identified Species: 26.67
UniProt: Q9NWT1 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NWT1 NP_060376.2 392 43964 S285 Q D K K V P P S L L C E I N T
Chimpanzee Pan troglodytes XP_518863 393 44017 S286 Q D K K V P P S L L C E V N T
Rhesus Macaque Macaca mulatta XP_001087458 392 43967 S285 Q D K K V P P S L L C E V N T
Dog Lupus familis XP_535884 391 43743 S287 Q D K K V P P S L L C E V K T
Cat Felis silvestris
Mouse Mus musculus Q9DCE5 382 42097 K280 M W T L P Q D K K V P P S L L
Rat Rattus norvegicus NP_001032433 382 42216 K280 M W T L T Q D K K A P P S L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514604 358 39493 Q257 I K M W Q F Q Q E K K T P P S
Chicken Gallus gallus Q5ZKU8 369 41214 N268 D G Y I K V W N L D L N K I N
Frog Xenopus laevis Q68FJ6 363 40513 S262 Q G T H V V V S S S S D G Y I
Zebra Danio Brachydanio rerio Q6TNS2 368 40882 L267 M K D D F C V L V T A S N D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181466 538 58474 N392 A R Y K I G D N I N I T C N S
Poplar Tree Populus trichocarpa XP_002318775 332 35851 S231 F T G G E D R S I T A W D V N
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176683 345 37437 G244 T A W D T N S G K L A Y S I E
Baker's Yeast Sacchar. cerevisiae P20484 468 53654 Y363 R I K D F K F Y T N E F G T Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 96.1 85.4 N.A. 72.4 75.2 N.A. 65 63 60.4 53 N.A. N.A. N.A. N.A. 27.7
Protein Similarity: 100 99.7 97.6 92.8 N.A. 83.9 83.4 N.A. 76.5 78.5 75 69.6 N.A. N.A. N.A. N.A. 44.8
P-Site Identity: 100 93.3 93.3 86.6 N.A. 0 0 N.A. 0 6.6 20 0 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 6.6 0 N.A. 6.6 13.3 26.6 13.3 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: 26.2 N.A. N.A. 27 20.9 N.A.
Protein Similarity: 46.1 N.A. N.A. 47.9 37.8 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: 13.3 N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 0 0 0 0 8 22 0 0 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 29 0 8 0 0 % C
% Asp: 8 29 8 22 0 8 22 0 0 8 0 8 8 8 0 % D
% Glu: 0 0 0 0 8 0 0 0 8 0 8 29 0 0 8 % E
% Phe: 8 0 0 0 15 8 8 0 0 0 0 8 0 0 0 % F
% Gly: 0 15 8 8 0 8 0 8 0 0 0 0 15 0 8 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 0 8 8 0 0 0 15 0 8 0 8 15 8 % I
% Lys: 0 15 36 36 8 8 0 15 22 8 8 0 8 8 0 % K
% Leu: 0 0 0 15 0 0 0 8 36 36 8 0 0 15 15 % L
% Met: 22 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 15 0 15 0 8 8 29 15 % N
% Pro: 0 0 0 0 8 29 29 0 0 0 15 15 8 8 0 % P
% Gln: 36 0 0 0 8 15 8 8 0 0 0 0 0 0 0 % Q
% Arg: 8 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 8 43 8 8 8 8 22 0 15 % S
% Thr: 8 8 22 0 15 0 0 0 8 15 0 15 0 8 29 % T
% Val: 0 0 0 0 36 15 15 0 8 8 0 0 22 8 0 % V
% Trp: 0 15 8 8 0 0 8 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 15 0 0 0 0 8 0 0 0 8 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _