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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK1IP1
All Species:
21.52
Human Site:
S358
Identified Species:
36.41
UniProt:
Q9NWT1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWT1
NP_060376.2
392
43964
S358
K
R
G
L
T
G
D
S
K
K
A
T
K
E
S
Chimpanzee
Pan troglodytes
XP_518863
393
44017
S359
K
R
G
L
T
G
D
S
K
K
A
T
K
E
S
Rhesus Macaque
Macaca mulatta
XP_001087458
392
43967
S358
K
R
S
L
A
G
D
S
K
K
A
T
K
E
S
Dog
Lupus familis
XP_535884
391
43743
S360
K
C
G
L
T
G
D
S
N
K
P
T
K
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCE5
382
42097
S353
K
S
D
V
S
G
D
S
K
Q
P
T
K
G
N
Rat
Rattus norvegicus
NP_001032433
382
42216
S353
K
S
D
H
T
G
G
S
Q
Q
P
T
K
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514604
358
39493
S330
R
E
K
E
D
S
V
S
T
K
S
Q
K
S
P
Chicken
Gallus gallus
Q5ZKU8
369
41214
K341
N
K
S
G
K
L
T
K
Q
R
R
R
I
V
P
Frog
Xenopus laevis
Q68FJ6
363
40513
E335
K
K
K
K
A
Q
N
E
T
T
D
K
E
A
S
Zebra Danio
Brachydanio rerio
Q6TNS2
368
40882
V340
V
P
V
R
S
K
R
V
R
I
L
G
E
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181466
538
58474
L465
A
A
V
I
M
F
I
L
V
L
M
S
M
V
A
Poplar Tree
Populus trichocarpa
XP_002318775
332
35851
K304
P
L
A
E
A
N
T
K
S
R
L
T
C
L
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176683
345
37437
A317
K
S
R
L
T
C
L
A
G
S
A
L
K
S
M
Baker's Yeast
Sacchar. cerevisiae
P20484
468
53654
T436
Q
S
E
V
E
S
D
T
E
E
L
K
K
I
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.1
85.4
N.A.
72.4
75.2
N.A.
65
63
60.4
53
N.A.
N.A.
N.A.
N.A.
27.7
Protein Similarity:
100
99.7
97.6
92.8
N.A.
83.9
83.4
N.A.
76.5
78.5
75
69.6
N.A.
N.A.
N.A.
N.A.
44.8
P-Site Identity:
100
100
86.6
66.6
N.A.
46.6
40
N.A.
20
0
13.3
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
86.6
73.3
N.A.
73.3
60
N.A.
33.3
20
33.3
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
26.2
N.A.
N.A.
27
20.9
N.A.
Protein Similarity:
46.1
N.A.
N.A.
47.9
37.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
33.3
13.3
N.A.
P-Site Similarity:
20
N.A.
N.A.
40
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
22
0
0
8
0
0
29
0
0
8
15
% A
% Cys:
0
8
0
0
0
8
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
15
0
8
0
43
0
0
0
8
0
0
0
0
% D
% Glu:
0
8
8
15
8
0
0
8
8
8
0
0
15
29
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
22
8
0
43
8
0
8
0
0
8
0
15
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
0
0
8
0
0
8
8
0
% I
% Lys:
58
15
15
8
8
8
0
15
29
36
0
15
65
0
0
% K
% Leu:
0
8
0
36
0
8
8
8
0
8
22
8
0
8
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
8
0
8
0
15
% M
% Asn:
8
0
0
0
0
8
8
0
8
0
0
0
0
0
22
% N
% Pro:
8
8
0
0
0
0
0
0
0
0
22
0
0
0
15
% P
% Gln:
8
0
0
0
0
8
0
0
15
15
0
8
0
0
0
% Q
% Arg:
8
22
8
8
0
0
8
0
8
15
8
8
0
8
0
% R
% Ser:
0
29
15
0
15
15
0
50
8
8
8
8
0
15
29
% S
% Thr:
0
0
0
0
36
0
15
8
15
8
0
50
0
0
0
% T
% Val:
8
0
15
15
0
0
8
8
8
0
0
0
0
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _