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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK1IP1 All Species: 21.52
Human Site: S358 Identified Species: 36.41
UniProt: Q9NWT1 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NWT1 NP_060376.2 392 43964 S358 K R G L T G D S K K A T K E S
Chimpanzee Pan troglodytes XP_518863 393 44017 S359 K R G L T G D S K K A T K E S
Rhesus Macaque Macaca mulatta XP_001087458 392 43967 S358 K R S L A G D S K K A T K E S
Dog Lupus familis XP_535884 391 43743 S360 K C G L T G D S N K P T K G N
Cat Felis silvestris
Mouse Mus musculus Q9DCE5 382 42097 S353 K S D V S G D S K Q P T K G N
Rat Rattus norvegicus NP_001032433 382 42216 S353 K S D H T G G S Q Q P T K R N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514604 358 39493 S330 R E K E D S V S T K S Q K S P
Chicken Gallus gallus Q5ZKU8 369 41214 K341 N K S G K L T K Q R R R I V P
Frog Xenopus laevis Q68FJ6 363 40513 E335 K K K K A Q N E T T D K E A S
Zebra Danio Brachydanio rerio Q6TNS2 368 40882 V340 V P V R S K R V R I L G E E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181466 538 58474 L465 A A V I M F I L V L M S M V A
Poplar Tree Populus trichocarpa XP_002318775 332 35851 K304 P L A E A N T K S R L T C L A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176683 345 37437 A317 K S R L T C L A G S A L K S M
Baker's Yeast Sacchar. cerevisiae P20484 468 53654 T436 Q S E V E S D T E E L K K I M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 96.1 85.4 N.A. 72.4 75.2 N.A. 65 63 60.4 53 N.A. N.A. N.A. N.A. 27.7
Protein Similarity: 100 99.7 97.6 92.8 N.A. 83.9 83.4 N.A. 76.5 78.5 75 69.6 N.A. N.A. N.A. N.A. 44.8
P-Site Identity: 100 100 86.6 66.6 N.A. 46.6 40 N.A. 20 0 13.3 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 86.6 73.3 N.A. 73.3 60 N.A. 33.3 20 33.3 26.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: 26.2 N.A. N.A. 27 20.9 N.A.
Protein Similarity: 46.1 N.A. N.A. 47.9 37.8 N.A.
P-Site Identity: 6.6 N.A. N.A. 33.3 13.3 N.A.
P-Site Similarity: 20 N.A. N.A. 40 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 0 22 0 0 8 0 0 29 0 0 8 15 % A
% Cys: 0 8 0 0 0 8 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 15 0 8 0 43 0 0 0 8 0 0 0 0 % D
% Glu: 0 8 8 15 8 0 0 8 8 8 0 0 15 29 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 22 8 0 43 8 0 8 0 0 8 0 15 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 8 0 0 8 0 0 8 8 0 % I
% Lys: 58 15 15 8 8 8 0 15 29 36 0 15 65 0 0 % K
% Leu: 0 8 0 36 0 8 8 8 0 8 22 8 0 8 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 8 0 8 0 15 % M
% Asn: 8 0 0 0 0 8 8 0 8 0 0 0 0 0 22 % N
% Pro: 8 8 0 0 0 0 0 0 0 0 22 0 0 0 15 % P
% Gln: 8 0 0 0 0 8 0 0 15 15 0 8 0 0 0 % Q
% Arg: 8 22 8 8 0 0 8 0 8 15 8 8 0 8 0 % R
% Ser: 0 29 15 0 15 15 0 50 8 8 8 8 0 15 29 % S
% Thr: 0 0 0 0 36 0 15 8 15 8 0 50 0 0 0 % T
% Val: 8 0 15 15 0 0 8 8 8 0 0 0 0 15 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _