Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK1IP1 All Species: 10
Human Site: S365 Identified Species: 16.92
UniProt: Q9NWT1 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NWT1 NP_060376.2 392 43964 S365 S K K A T K E S G L I S T K K
Chimpanzee Pan troglodytes XP_518863 393 44017 S366 S K K A T K E S G L V S T K K
Rhesus Macaque Macaca mulatta XP_001087458 392 43967 S365 S K K A T K E S G L V S T K K
Dog Lupus familis XP_535884 391 43743 N367 S N K P T K G N T V V S T K K
Cat Felis silvestris
Mouse Mus musculus Q9DCE5 382 42097 N360 S K Q P T K G N S P V T A K K
Rat Rattus norvegicus NP_001032433 382 42216 N360 S Q Q P T K R N S P A P A K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514604 358 39493 P337 S T K S Q K S P K K R K L E S
Chicken Gallus gallus Q5ZKU8 369 41214 P348 K Q R R R I V P A K R K L E A
Frog Xenopus laevis Q68FJ6 363 40513 S342 E T T D K E A S E T Q V V H K
Zebra Danio Brachydanio rerio Q6TNS2 368 40882 V347 V R I L G E E V I M E D E K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181466 538 58474 A472 L V L M S M V A F S I S V K G
Poplar Tree Populus trichocarpa XP_002318775 332 35851 A311 K S R L T C L A G S S H N V S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176683 345 37437 M324 A G S A L K S M R R P Q I G K
Baker's Yeast Sacchar. cerevisiae P20484 468 53654 M443 T E E L K K I M F G E K K K L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 96.1 85.4 N.A. 72.4 75.2 N.A. 65 63 60.4 53 N.A. N.A. N.A. N.A. 27.7
Protein Similarity: 100 99.7 97.6 92.8 N.A. 83.9 83.4 N.A. 76.5 78.5 75 69.6 N.A. N.A. N.A. N.A. 44.8
P-Site Identity: 100 93.3 93.3 53.3 N.A. 40 33.3 N.A. 20 0 13.3 13.3 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 73.3 N.A. 66.6 53.3 N.A. 33.3 20 20 33.3 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: 26.2 N.A. N.A. 27 20.9 N.A.
Protein Similarity: 46.1 N.A. N.A. 47.9 37.8 N.A.
P-Site Identity: 13.3 N.A. N.A. 20 13.3 N.A.
P-Site Similarity: 26.6 N.A. N.A. 26.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 29 0 0 8 15 8 0 8 0 15 0 8 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % D
% Glu: 8 8 8 0 0 15 29 0 8 0 15 0 8 15 0 % E
% Phe: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 8 0 15 0 29 8 0 0 0 8 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % H
% Ile: 0 0 8 0 0 8 8 0 8 0 15 0 8 0 0 % I
% Lys: 15 29 36 0 15 65 0 0 8 15 0 22 8 65 58 % K
% Leu: 8 0 8 22 8 0 8 0 0 22 0 0 15 0 8 % L
% Met: 0 0 0 8 0 8 0 15 0 8 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 22 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 22 0 0 0 15 0 15 8 8 0 0 0 % P
% Gln: 0 15 15 0 8 0 0 0 0 0 8 8 0 0 0 % Q
% Arg: 0 8 15 8 8 0 8 0 8 8 15 0 0 0 0 % R
% Ser: 50 8 8 8 8 0 15 29 15 15 8 36 0 0 15 % S
% Thr: 8 15 8 0 50 0 0 0 8 8 0 8 29 0 0 % T
% Val: 8 8 0 0 0 0 15 8 0 8 29 8 15 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _