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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAK1IP1 All Species: 28.48
Human Site: S46 Identified Species: 48.21
UniProt: Q9NWT1 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NWT1 NP_060376.2 392 43964 S46 H A H T A S L S A V A V N S R
Chimpanzee Pan troglodytes XP_518863 393 44017 S47 H A H T A S L S A V A V N S R
Rhesus Macaque Macaca mulatta XP_001087458 392 43967 S46 H A H T A S L S A V A V N S R
Dog Lupus familis XP_535884 391 43743 S48 H A H T A S L S A V A V N S R
Cat Felis silvestris
Mouse Mus musculus Q9DCE5 382 42097 S46 H S H T A S L S V L A S N S R
Rat Rattus norvegicus NP_001032433 382 42216 S46 H A H T A S L S A V A A N N R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514604 358 39493 V34 V A V N D R F V V T G S K D E
Chicken Gallus gallus Q5ZKU8 369 41214 S39 H A H T A S L S A V A V N S K
Frog Xenopus laevis Q68FJ6 363 40513 A38 S A D F T H H A H T A S V S V
Zebra Danio Brachydanio rerio Q6TNS2 368 40882 T42 W T I E P T F T H H A H T A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181466 538 58474 K50 N A H T G C I K S L A A S S R
Poplar Tree Populus trichocarpa XP_002318775 332 35851 Y8 M S L I A G S Y E K F I W G F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176683 345 37437 K21 G F K L K P T K H D A E S Q T
Baker's Yeast Sacchar. cerevisiae P20484 468 53654 K110 Q A H S L S I K C L A V S R R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 96.1 85.4 N.A. 72.4 75.2 N.A. 65 63 60.4 53 N.A. N.A. N.A. N.A. 27.7
Protein Similarity: 100 99.7 97.6 92.8 N.A. 83.9 83.4 N.A. 76.5 78.5 75 69.6 N.A. N.A. N.A. N.A. 44.8
P-Site Identity: 100 100 100 100 N.A. 73.3 86.6 N.A. 6.6 93.3 20 6.6 N.A. N.A. N.A. N.A. 40
P-Site Similarity: 100 100 100 100 N.A. 86.6 93.3 N.A. 6.6 100 26.6 26.6 N.A. N.A. N.A. N.A. 73.3
Percent
Protein Identity: 26.2 N.A. N.A. 27 20.9 N.A.
Protein Similarity: 46.1 N.A. N.A. 47.9 37.8 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 40 N.A.
P-Site Similarity: 20 N.A. N.A. 13.3 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 72 0 0 58 0 0 8 43 0 86 15 0 8 0 % A
% Cys: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 8 0 0 0 0 8 0 0 0 8 0 % D
% Glu: 0 0 0 8 0 0 0 0 8 0 0 8 0 0 8 % E
% Phe: 0 8 0 8 0 0 15 0 0 0 8 0 0 0 8 % F
% Gly: 8 0 0 0 8 8 0 0 0 0 8 0 0 8 0 % G
% His: 50 0 65 0 0 8 8 0 22 8 0 8 0 0 0 % H
% Ile: 0 0 8 8 0 0 15 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 8 0 8 0 0 22 0 8 0 0 8 0 8 % K
% Leu: 0 0 8 8 8 0 50 0 0 22 0 0 0 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 8 0 0 0 0 0 0 0 0 50 8 0 % N
% Pro: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 58 % R
% Ser: 8 15 0 8 0 58 8 50 8 0 0 22 22 58 8 % S
% Thr: 0 8 0 58 8 8 8 8 0 15 0 0 8 0 8 % T
% Val: 8 0 8 0 0 0 0 8 15 43 0 43 8 0 8 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _