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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AURKAIP1 All Species: 1.21
Human Site: S41 Identified Species: 2.96
UniProt: Q9NWT8 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NWT8 NP_001120701.1 199 22354 S41 C G P L Y S T S P A G P G R A
Chimpanzee Pan troglodytes XP_514409 731 81566 P573 C G P L Y S T P P A G P G R A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848734 198 22891 Q40 C R P C Y S T Q P A R P S G V
Cat Felis silvestris
Mouse Mus musculus Q9DCJ7 200 23310 Q42 F R P L Y S L Q P A S P S R A
Rat Rattus norvegicus NP_001004237 200 23372 Q42 F R P L Y S L Q P A S P S R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510434 204 22527 R40 G T R A H S S R P A D G Q S R
Chicken Gallus gallus NP_001026043 202 23395 N46 C T Q P P N K N G A Q P Q R W
Frog Xenopus laevis NP_001090287 197 23283 Q41 L C A G Y S S Q L T Q R Q Q V
Zebra Danio Brachydanio rerio NP_001099165 209 24109 N55 C F T S A A D N T L P P K L W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_800134 285 32130 S52 Q E T L K V L S P S L S A V L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.9 N.A. 75.3 N.A. 69.5 71.5 N.A. 52.9 51.4 45.7 41.6 N.A. N.A. N.A. N.A. 23.5
Protein Similarity: 100 26.9 N.A. 82.9 N.A. 77 80.5 N.A. 66.1 64.3 61.8 54 N.A. N.A. N.A. N.A. 36.1
P-Site Identity: 100 93.3 N.A. 53.3 N.A. 60 60 N.A. 20 26.6 13.3 13.3 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 93.3 N.A. 53.3 N.A. 60 60 N.A. 33.3 40 26.6 26.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 10 10 0 0 0 70 0 0 10 0 40 % A
% Cys: 50 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 20 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 20 0 10 0 0 0 0 10 0 20 10 20 10 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 0 10 0 0 0 0 0 10 0 0 % K
% Leu: 10 0 0 50 0 0 30 0 10 10 10 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 20 0 0 0 0 0 0 0 % N
% Pro: 0 0 50 10 10 0 0 10 70 0 10 70 0 0 0 % P
% Gln: 10 0 10 0 0 0 0 40 0 0 20 0 30 10 0 % Q
% Arg: 0 30 10 0 0 0 0 10 0 0 10 10 0 50 10 % R
% Ser: 0 0 0 10 0 70 20 20 0 10 20 10 30 10 0 % S
% Thr: 0 20 20 0 0 0 30 0 10 10 0 0 0 0 0 % T
% Val: 0 0 0 0 0 10 0 0 0 0 0 0 0 10 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % W
% Tyr: 0 0 0 0 60 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _