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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AURKAIP1 All Species: 26.06
Human Site: T191 Identified Species: 63.7
UniProt: Q9NWT8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NWT8 NP_001120701.1 199 22354 T191 E A P E G W Q T P K I Y L R G
Chimpanzee Pan troglodytes XP_514409 731 81566 T723 E A P E G W Q T P K I Y L R G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848734 198 22891 T190 E A P A G W Q T P K I Y L K G
Cat Felis silvestris
Mouse Mus musculus Q9DCJ7 200 23310 T192 E A P E N W Q T P K I Y L K N
Rat Rattus norvegicus NP_001004237 200 23372 T192 E A P E N W Q T P K I Y M K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510434 204 22527 T196 E A P E G W H T P K V Y V K G
Chicken Gallus gallus NP_001026043 202 23395 T192 S P P A G W Q T P K I F L R S
Frog Xenopus laevis NP_001090287 197 23283 V190 K A P D G W Q V P K I Y V K H
Zebra Danio Brachydanio rerio NP_001099165 209 24109 V198 K A P E G C T V P K I Y V R V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_800134 285 32130 S251 K E I S P E E S K K R Q K K G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.9 N.A. 75.3 N.A. 69.5 71.5 N.A. 52.9 51.4 45.7 41.6 N.A. N.A. N.A. N.A. 23.5
Protein Similarity: 100 26.9 N.A. 82.9 N.A. 77 80.5 N.A. 66.1 64.3 61.8 54 N.A. N.A. N.A. N.A. 36.1
P-Site Identity: 100 100 N.A. 86.6 N.A. 80 73.3 N.A. 73.3 66.6 60 60 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 N.A. 93.3 N.A. 86.6 86.6 N.A. 93.3 73.3 86.6 73.3 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 80 0 20 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 60 10 0 60 0 10 10 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 0 0 0 0 70 0 0 0 0 0 0 0 0 0 50 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 80 0 0 0 0 % I
% Lys: 30 0 0 0 0 0 0 0 10 100 0 0 10 60 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 50 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 20 % N
% Pro: 0 10 90 0 10 0 0 0 90 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 70 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 10 0 0 40 0 % R
% Ser: 10 0 0 10 0 0 0 10 0 0 0 0 0 0 10 % S
% Thr: 0 0 0 0 0 0 10 70 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 20 0 0 10 0 30 0 10 % V
% Trp: 0 0 0 0 0 80 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 80 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _