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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRPL22
All Species:
29.09
Human Site:
S36
Identified Species:
58.18
UniProt:
Q9NWU5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWU5
NP_001014990.1
206
23641
S36
P
Q
S
Y
I
H
T
S
A
S
L
D
I
S
R
Chimpanzee
Pan troglodytes
XP_001170128
206
23694
S36
P
Q
S
Y
I
H
T
S
A
S
L
D
I
S
R
Rhesus Macaque
Macaca mulatta
XP_001113082
206
23657
S36
P
Q
S
Y
I
H
T
S
A
S
L
D
I
S
R
Dog
Lupus familis
XP_536458
347
38906
S177
P
Q
S
Y
I
H
T
S
G
S
L
D
I
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BU88
206
23786
S36
P
P
S
C
I
H
T
S
A
S
L
D
I
S
R
Rat
Rattus norvegicus
P0C2C0
206
24021
S36
P
Q
S
C
I
H
T
S
T
S
L
D
I
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508680
220
24592
S50
P
L
S
H
I
H
T
S
A
S
L
D
A
S
F
Chicken
Gallus gallus
XP_414573
208
23845
S38
P
L
S
C
I
H
T
S
T
S
L
Q
K
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666099
209
24223
T40
S
Q
V
S
C
L
H
T
S
S
E
L
N
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXB5
233
26934
N61
G
M
L
C
A
K
W
N
K
Y
N
Y
G
P
R
Honey Bee
Apis mellifera
XP_396572
211
24892
D38
Y
Y
Y
F
K
S
D
D
E
D
D
D
V
K
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796402
243
27404
V74
S
L
T
Q
R
S
F
V
H
T
S
S
N
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
95.1
54.1
N.A.
89.3
89.3
N.A.
72.2
73.5
N.A.
67.4
N.A.
42.4
39.3
N.A.
43.6
Protein Similarity:
100
99.5
98
57.3
N.A.
93.1
93.1
N.A.
81.8
81.7
N.A.
80.3
N.A.
57.5
58.7
N.A.
57.6
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
73.3
53.3
N.A.
13.3
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
80
53.3
N.A.
40
N.A.
13.3
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
42
0
0
0
9
0
0
% A
% Cys:
0
0
0
34
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
9
0
9
9
67
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
17
% F
% Gly:
9
0
0
0
0
0
0
0
9
0
0
0
9
0
9
% G
% His:
0
0
0
9
0
67
9
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
67
0
0
0
0
0
0
0
50
0
0
% I
% Lys:
0
0
0
0
9
9
0
0
9
0
0
0
9
9
9
% K
% Leu:
0
25
9
0
0
9
0
0
0
0
67
9
0
9
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
9
0
17
9
9
% N
% Pro:
67
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
50
0
9
0
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
59
% R
% Ser:
17
0
67
9
0
17
0
67
9
75
9
9
0
67
0
% S
% Thr:
0
0
9
0
0
0
67
9
17
9
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
9
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
9
34
0
0
0
0
0
9
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _