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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRPL22
All Species:
30
Human Site:
Y152
Identified Species:
60
UniProt:
Q9NWU5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWU5
NP_001014990.1
206
23641
Y152
Q
C
L
K
R
I
R
Y
H
G
R
G
R
F
G
Chimpanzee
Pan troglodytes
XP_001170128
206
23694
Y152
Q
C
L
K
R
I
R
Y
H
G
R
G
R
F
G
Rhesus Macaque
Macaca mulatta
XP_001113082
206
23657
Y152
Q
C
L
K
R
I
R
Y
H
G
R
G
H
F
G
Dog
Lupus familis
XP_536458
347
38906
Y293
Q
Y
L
K
R
I
R
Y
H
G
R
G
R
F
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BU88
206
23786
Y152
Q
C
L
K
R
I
R
Y
H
G
R
G
R
F
G
Rat
Rattus norvegicus
P0C2C0
206
24021
Y152
Q
C
L
K
R
I
R
Y
H
G
R
G
R
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508680
220
24592
Y166
Q
Y
L
K
R
I
R
Y
H
G
R
G
G
F
G
Chicken
Gallus gallus
XP_414573
208
23845
L154
H
Y
T
K
R
I
R
L
H
G
K
G
M
F
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666099
209
24223
Y156
K
Y
L
K
R
I
R
Y
H
G
R
G
M
F
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXB5
233
26934
R177
R
V
F
K
G
V
R
R
H
A
R
G
R
F
G
Honey Bee
Apis mellifera
XP_396572
211
24892
R154
E
V
I
K
G
I
R
R
H
A
R
S
R
I
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796402
243
27404
F190
K
Y
Q
H
A
I
R
F
H
A
K
G
R
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
95.1
54.1
N.A.
89.3
89.3
N.A.
72.2
73.5
N.A.
67.4
N.A.
42.4
39.3
N.A.
43.6
Protein Similarity:
100
99.5
98
57.3
N.A.
93.1
93.1
N.A.
81.8
81.7
N.A.
80.3
N.A.
57.5
58.7
N.A.
57.6
P-Site Identity:
100
100
93.3
93.3
N.A.
100
100
N.A.
86.6
60
N.A.
80
N.A.
53.3
46.6
N.A.
33.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
100
100
N.A.
86.6
66.6
N.A.
86.6
N.A.
66.6
60
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
25
0
0
0
9
0
% A
% Cys:
0
42
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
9
0
0
0
0
0
84
0
% F
% Gly:
0
0
0
0
17
0
0
0
0
75
0
92
9
0
92
% G
% His:
9
0
0
9
0
0
0
0
100
0
0
0
9
0
0
% H
% Ile:
0
0
9
0
0
92
0
0
0
0
0
0
0
9
0
% I
% Lys:
17
0
0
92
0
0
0
0
0
0
17
0
0
0
0
% K
% Leu:
0
0
67
0
0
0
0
9
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
59
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
75
0
100
17
0
0
84
0
67
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
17
0
0
0
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
42
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _