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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MERIT40 All Species: 25.15
Human Site: S177 Identified Species: 61.48
UniProt: Q9NWV8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NWV8 NP_001028721.1 329 36560 S177 L Y D L E T A S C S T F N L E
Chimpanzee Pan troglodytes XP_512482 329 36513 S177 L Y D L E T A S C S T F N L E
Rhesus Macaque Macaca mulatta XP_001113414 329 36525 S177 L Y D L E T A S C S T F N L E
Dog Lupus familis XP_533881 336 37413 S184 L Y D L E T A S C S T F N L E
Cat Felis silvestris
Mouse Mus musculus Q3UI43 333 36775 S181 L Y D L E T A S C S T F N L E
Rat Rattus norvegicus Q5XIJ6 334 36860 S182 L Y D L E T A S C S T F N L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6DJG6 328 36935 V178 L Y D L E T N V C E S F N L E
Zebra Danio Brachydanio rerio Q6AXK4 370 40883 V219 L Y D L E T N V C E S F N L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120759 190 21723 L53 K S Y D L G Q L F D E I Q Q K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793273 338 38040 T198 M F D L T S E T R D C E S C D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.7 93.1 N.A. 89.7 88.3 N.A. N.A. N.A. 72.3 58.9 N.A. N.A. 23.7 N.A. 35.2
Protein Similarity: 100 99.3 99 94.9 N.A. 94.5 94 N.A. N.A. N.A. 81.1 69.7 N.A. N.A. 37.9 N.A. 52.6
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 73.3 73.3 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 80 80 N.A. N.A. 6.6 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 60 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 80 0 10 0 0 10 0 % C
% Asp: 0 0 90 10 0 0 0 0 0 20 0 0 0 0 10 % D
% Glu: 0 0 0 0 80 0 10 0 0 20 10 10 0 0 80 % E
% Phe: 0 10 0 0 0 0 0 0 10 0 0 80 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 80 0 0 90 10 0 0 10 0 0 0 0 0 80 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 20 0 0 0 0 0 80 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 10 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 0 10 0 0 0 10 0 60 0 60 20 0 10 0 0 % S
% Thr: 0 0 0 0 10 80 0 10 0 0 60 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 80 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _