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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THG1L
All Species:
30
Human Site:
S108
Identified Species:
50.77
UniProt:
Q9NWX6
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWX6
NP_060342.2
298
34831
S108
Y
G
Q
S
D
E
Y
S
F
V
F
K
R
K
T
Chimpanzee
Pan troglodytes
XP_518066
298
34800
S108
Y
G
Q
S
D
E
Y
S
F
V
F
K
R
K
T
Rhesus Macaque
Macaca mulatta
XP_001113603
298
34781
S108
Y
G
Q
S
D
E
Y
S
F
V
F
K
R
K
T
Dog
Lupus familis
XP_536453
398
45751
S208
Y
G
Q
S
D
E
Y
S
F
V
F
K
R
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CY52
298
34952
S108
Y
G
Q
S
D
E
Y
S
F
V
F
R
K
K
S
Rat
Rattus norvegicus
Q5M965
298
34831
S108
Y
G
Q
S
D
E
Y
S
F
V
F
R
K
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507734
269
31692
K90
K
K
M
S
N
W
F
K
R
R
A
S
K
F
M
Chicken
Gallus gallus
NP_001025787
269
31994
K90
K
K
K
S
K
W
F
K
R
R
A
S
K
F
M
Frog
Xenopus laevis
NP_001088597
286
33655
S96
F
G
Q
S
D
E
Y
S
F
V
F
H
K
K
S
Zebra Danio
Brachydanio rerio
NP_001007456
269
31543
K90
K
R
S
T
N
W
F
K
R
R
A
S
K
L
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3N8
286
33054
L97
K
R
R
S
A
K
L
L
T
Y
V
T
S
L
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792143
265
30598
T87
F
V
M
K
K
D
T
T
Q
Y
G
R
R
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53215
237
27738
K59
K
L
M
N
A
C
A
K
N
L
V
L
K
Y
K
Red Bread Mold
Neurospora crassa
Q7SDM8
293
33586
S98
R
R
A
S
K
L
V
S
T
I
V
S
T
F
T
Conservation
Percent
Protein Identity:
100
98.9
96.9
68
N.A.
82.2
84.2
N.A.
77.5
76.1
59.4
63.7
N.A.
48.6
N.A.
N.A.
51
Protein Similarity:
100
98.9
97.3
71.6
N.A.
89.5
90.9
N.A.
82.8
82.5
73.1
75.5
N.A.
64.4
N.A.
N.A.
66.1
P-Site Identity:
100
100
100
93.3
N.A.
80
73.3
N.A.
6.6
6.6
73.3
0
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
26.6
93.3
26.6
N.A.
20
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
40.6
47.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.3
63
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
15
0
8
0
0
0
22
0
0
8
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
50
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% E
% Phe:
15
0
0
0
0
0
22
0
50
0
50
0
0
22
8
% F
% Gly:
0
50
0
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
36
15
8
8
22
8
0
29
0
0
0
29
50
43
8
% K
% Leu:
0
8
0
0
0
8
8
8
0
8
0
8
0
15
0
% L
% Met:
0
0
22
0
0
0
0
0
0
0
0
0
0
0
22
% M
% Asn:
0
0
0
8
15
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
50
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
8
22
8
0
0
0
0
0
22
22
0
22
36
8
0
% R
% Ser:
0
0
8
79
0
0
0
58
0
0
0
29
8
0
36
% S
% Thr:
0
0
0
8
0
0
8
8
15
0
0
8
8
0
29
% T
% Val:
0
8
0
0
0
0
8
0
0
50
22
0
0
0
0
% V
% Trp:
0
0
0
0
0
22
0
0
0
0
0
0
0
0
0
% W
% Tyr:
43
0
0
0
0
0
50
0
0
15
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _