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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THG1L
All Species:
21.21
Human Site:
T272
Identified Species:
35.9
UniProt:
Q9NWX6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWX6
NP_060342.2
298
34831
T272
M
A
V
T
R
T
R
T
K
P
V
P
L
H
C
Chimpanzee
Pan troglodytes
XP_518066
298
34800
T272
M
A
V
T
R
T
R
T
K
P
V
P
L
H
C
Rhesus Macaque
Macaca mulatta
XP_001113603
298
34781
T272
M
A
V
T
R
T
R
T
K
P
V
P
L
H
C
Dog
Lupus familis
XP_536453
398
45751
T372
M
A
V
T
R
T
R
T
K
P
V
P
L
Y
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9CY52
298
34952
T272
K
A
V
A
R
T
R
T
R
V
V
A
L
N
C
Rat
Rattus norvegicus
Q5M965
298
34831
T272
M
A
V
T
R
T
R
T
K
L
V
A
L
N
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507734
269
31692
G254
P
L
H
C
D
I
I
G
D
A
F
W
K
E
H
Chicken
Gallus gallus
NP_001025787
269
31994
G254
P
L
H
C
D
I
I
G
E
Q
F
W
E
E
Y
Frog
Xenopus laevis
NP_001088597
286
33655
N260
V
E
V
S
R
W
R
N
E
I
V
E
L
H
C
Zebra Danio
Brachydanio rerio
NP_001007456
269
31543
D254
H
S
C
D
V
I
G
D
Q
F
W
D
E
H
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3N8
286
33054
P261
Y
D
A
P
Q
T
F
P
R
L
V
E
M
Q
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792143
265
30598
S251
H
K
D
I
I
G
N
S
F
W
T
E
H
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53215
237
27738
H223
T
R
K
G
E
I
L
H
I
N
V
I
A
Q
I
Red Bread Mold
Neurospora crassa
Q7SDM8
293
33586
I262
K
V
R
T
K
A
K
I
V
V
E
H
L
D
I
Conservation
Percent
Protein Identity:
100
98.9
96.9
68
N.A.
82.2
84.2
N.A.
77.5
76.1
59.4
63.7
N.A.
48.6
N.A.
N.A.
51
Protein Similarity:
100
98.9
97.3
71.6
N.A.
89.5
90.9
N.A.
82.8
82.5
73.1
75.5
N.A.
64.4
N.A.
N.A.
66.1
P-Site Identity:
100
100
100
93.3
N.A.
60
80
N.A.
0
0
46.6
6.6
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
73.3
86.6
N.A.
0
6.6
66.6
20
N.A.
33.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
40.6
47.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.3
63
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
43
8
8
0
8
0
0
0
8
0
15
8
0
0
% A
% Cys:
0
0
8
15
0
0
0
0
0
0
0
0
0
0
50
% C
% Asp:
0
8
8
8
15
0
0
8
8
0
0
8
0
8
0
% D
% Glu:
0
8
0
0
8
0
0
0
15
0
8
22
15
15
8
% E
% Phe:
0
0
0
0
0
0
8
0
8
8
15
0
0
0
0
% F
% Gly:
0
0
0
8
0
8
8
15
0
0
0
0
0
0
0
% G
% His:
15
0
15
0
0
0
0
8
0
0
0
8
8
36
8
% H
% Ile:
0
0
0
8
8
29
15
8
8
8
0
8
0
0
22
% I
% Lys:
15
8
8
0
8
0
8
0
36
0
0
0
8
0
0
% K
% Leu:
0
15
0
0
0
0
8
0
0
15
0
0
58
0
0
% L
% Met:
36
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
8
8
0
8
0
0
0
15
0
% N
% Pro:
15
0
0
8
0
0
0
8
0
29
0
29
0
8
8
% P
% Gln:
0
0
0
0
8
0
0
0
8
8
0
0
0
15
0
% Q
% Arg:
0
8
8
0
50
0
50
0
15
0
0
0
0
0
0
% R
% Ser:
0
8
0
8
0
0
0
8
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
43
0
50
0
43
0
0
8
0
0
0
0
% T
% Val:
8
8
50
0
8
0
0
0
8
15
65
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
8
8
15
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _