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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TXNL4B All Species: 4.55
Human Site: S50 Identified Species: 7.69
UniProt: Q9NX01 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NX01 NP_001135789.1 149 17015 S50 D I L S K T S S D L S K M A A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103949 149 17022 S50 D I L S K T S S D L S K M A A
Dog Lupus familis XP_853407 149 17054 P50 D I L S K T S P D L S K M A A
Cat Felis silvestris
Mouse Mus musculus Q8BUH1 149 16875 A50 D I L S K T S A D L S K M A A
Rat Rattus norvegicus NP_001013913 149 17036 A50 D I L S K T S A D L S K M A T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416612 149 16980 H50 D I L A K T A H D L S K M A V
Frog Xenopus laevis NP_001089306 149 17095 H50 D I L S K T S H D L S K M A S
Zebra Danio Brachydanio rerio NP_001032200 149 17015 H50 E I L S K T A H D L S N M A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624360 142 16840 V44 M C M K M D E V L Y N I A E K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780032 149 17110 E50 E I L S K T S E D L G K M A D
Poplar Tree Populus trichocarpa XP_002298799 153 17406 V54 L S K S A R E V S K F A T I A
Maize Zea mays NP_001147284 152 17193 I53 L D K S S W D I S K F A M V A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_189117 159 18300 V60 L A K S V R D V S K F A K V A
Baker's Yeast Sacchar. cerevisiae Q06819 143 16758 D43 D R Q C M I M D E L L S S I A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.3 97.3 N.A. 95.3 97.9 N.A. N.A. 89.2 89.2 83.8 N.A. N.A. 36.9 N.A. 73.8
Protein Similarity: 100 N.A. 99.3 97.3 N.A. 96.6 98.6 N.A. N.A. 93.2 95.9 93.2 N.A. N.A. 63 N.A. 87.2
P-Site Identity: 100 N.A. 100 93.3 N.A. 93.3 86.6 N.A. N.A. 73.3 86.6 66.6 N.A. N.A. 0 N.A. 73.3
P-Site Similarity: 100 N.A. 100 93.3 N.A. 100 93.3 N.A. N.A. 86.6 93.3 86.6 N.A. N.A. 13.3 N.A. 80
Percent
Protein Identity: 58.1 58.5 N.A. 56.6 31.5 N.A.
Protein Similarity: 74.5 76.3 N.A. 74.8 59 N.A.
P-Site Identity: 13.3 20 N.A. 13.3 20 N.A.
P-Site Similarity: 13.3 20 N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 8 0 15 15 0 0 0 22 8 65 58 % A
% Cys: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 58 8 0 0 0 8 15 8 65 0 0 0 0 0 8 % D
% Glu: 15 0 0 0 0 0 15 8 8 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 22 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 22 0 0 0 0 0 0 0 % H
% Ile: 0 65 0 0 0 8 0 8 0 0 0 8 0 15 0 % I
% Lys: 0 0 22 8 65 0 0 0 0 22 0 58 8 0 8 % K
% Leu: 22 0 65 0 0 0 0 0 8 72 8 0 0 0 0 % L
% Met: 8 0 8 0 15 0 8 0 0 0 0 0 72 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 0 15 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 0 79 8 0 50 15 22 0 58 8 8 0 15 % S
% Thr: 0 0 0 0 0 65 0 0 0 0 0 0 8 0 8 % T
% Val: 0 0 0 0 8 0 0 22 0 0 0 0 0 15 8 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _