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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TXNL4B All Species: 39.7
Human Site: Y72 Identified Species: 67.18
UniProt: Q9NX01 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NX01 NP_001135789.1 149 17015 Y72 Q T A V Y T Q Y F D I S Y I P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103949 149 17022 Y72 Q T P V Y T Q Y F D I S Y I P
Dog Lupus familis XP_853407 149 17054 Y72 Q T P V Y T H Y F D I S Y I P
Cat Felis silvestris
Mouse Mus musculus Q8BUH1 149 16875 Y72 H T P V Y T Q Y F D I S Y I P
Rat Rattus norvegicus NP_001013913 149 17036 Y72 Q T P V Y T Q Y F D I S Y I P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416612 149 16980 Y72 K V P V Y T Q Y F D I S Y I P
Frog Xenopus laevis NP_001089306 149 17095 Y72 K V P V Y T Q Y F D I S Y I P
Zebra Danio Brachydanio rerio NP_001032200 149 17015 Y72 S A P V Y S R Y F D I S F I P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624360 142 16840 V66 Y L V D I T Q V P D F N K M Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780032 149 17110 Y72 S I P V Y T Q Y F D I T L I P
Poplar Tree Populus trichocarpa XP_002298799 153 17406 Y76 D V Q V Y V N Y F D I T L V P
Maize Zea mays NP_001147284 152 17193 Y75 E I Q V Y I D Y F D I T L V P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_189117 159 18300 Y82 D V Q V Y V K Y F D I T L F P
Baker's Yeast Sacchar. cerevisiae Q06819 143 16758 D65 V I Y L C D I D E V S D F D E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.3 97.3 N.A. 95.3 97.9 N.A. N.A. 89.2 89.2 83.8 N.A. N.A. 36.9 N.A. 73.8
Protein Similarity: 100 N.A. 99.3 97.3 N.A. 96.6 98.6 N.A. N.A. 93.2 95.9 93.2 N.A. N.A. 63 N.A. 87.2
P-Site Identity: 100 N.A. 93.3 86.6 N.A. 86.6 93.3 N.A. N.A. 80 80 60 N.A. N.A. 20 N.A. 66.6
P-Site Similarity: 100 N.A. 93.3 86.6 N.A. 86.6 93.3 N.A. N.A. 86.6 86.6 80 N.A. N.A. 33.3 N.A. 73.3
Percent
Protein Identity: 58.1 58.5 N.A. 56.6 31.5 N.A.
Protein Similarity: 74.5 76.3 N.A. 74.8 59 N.A.
P-Site Identity: 46.6 46.6 N.A. 46.6 0 N.A.
P-Site Similarity: 60 66.6 N.A. 60 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 0 0 8 0 8 8 8 0 93 0 8 0 8 0 % D
% Glu: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 86 0 8 0 15 8 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 22 0 0 8 8 8 0 0 0 86 0 0 65 0 % I
% Lys: 15 0 0 0 0 0 8 0 0 0 0 0 8 0 0 % K
% Leu: 0 8 0 8 0 0 0 0 0 0 0 0 29 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 58 0 0 0 0 0 8 0 0 0 0 0 86 % P
% Gln: 29 0 22 0 0 0 58 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % R
% Ser: 15 0 0 0 0 8 0 0 0 0 8 58 0 0 0 % S
% Thr: 0 36 0 0 0 65 0 0 0 0 0 29 0 0 0 % T
% Val: 8 29 8 86 0 15 0 8 0 8 0 0 0 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 8 0 86 0 0 86 0 0 0 0 50 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _