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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COMMD8
All Species:
19.7
Human Site:
S157
Identified Species:
61.9
UniProt:
Q9NX08
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX08
NP_060315.1
183
21090
S157
N
G
E
V
K
P
Y
S
I
E
M
S
R
E
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532368
183
20969
S157
N
G
E
V
K
P
Y
S
V
E
M
S
K
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZG3
183
20833
T157
D
D
K
V
K
P
Y
T
V
E
M
S
K
E
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420723
259
29369
S233
N
G
E
I
K
P
I
S
I
E
M
N
K
E
E
Frog
Xenopus laevis
NP_001088208
183
20321
S157
N
G
S
V
T
P
V
S
V
E
M
N
K
E
E
Zebra Danio
Brachydanio rerio
NP_001071186
176
19946
N150
N
G
I
Q
R
S
V
N
I
E
M
N
K
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121317
179
21096
K155
M
L
E
S
K
N
S
K
R
I
L
D
M
E
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789228
183
20524
S156
D
G
T
N
R
L
V
S
L
E
L
D
K
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
85.7
N.A.
76.5
N.A.
N.A.
N.A.
47
57.9
47.5
N.A.
N.A.
29.5
N.A.
38.8
Protein Similarity:
100
N.A.
N.A.
93.4
N.A.
86.8
N.A.
N.A.
N.A.
57.1
74.8
68.3
N.A.
N.A.
54
N.A.
62.3
P-Site Identity:
100
N.A.
N.A.
86.6
N.A.
60
N.A.
N.A.
N.A.
73.3
60
46.6
N.A.
N.A.
20
N.A.
33.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
N.A.
N.A.
N.A.
93.3
80
73.3
N.A.
N.A.
26.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
25
13
0
0
0
0
0
0
0
0
0
25
0
0
0
% D
% Glu:
0
0
50
0
0
0
0
0
0
88
0
0
0
100
88
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
75
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
13
13
0
0
13
0
38
13
0
0
0
0
0
% I
% Lys:
0
0
13
0
63
0
0
13
0
0
0
0
75
0
0
% K
% Leu:
0
13
0
0
0
13
0
0
13
0
25
0
0
0
13
% L
% Met:
13
0
0
0
0
0
0
0
0
0
75
0
13
0
0
% M
% Asn:
63
0
0
13
0
13
0
13
0
0
0
38
0
0
0
% N
% Pro:
0
0
0
0
0
63
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
25
0
0
0
13
0
0
0
13
0
0
% R
% Ser:
0
0
13
13
0
13
13
63
0
0
0
38
0
0
0
% S
% Thr:
0
0
13
0
13
0
0
13
0
0
0
0
0
0
0
% T
% Val:
0
0
0
50
0
0
38
0
38
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
38
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _