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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDIT4 All Species: 13.64
Human Site: S46 Identified Species: 25
UniProt: Q9NX09 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NX09 NP_061931.1 232 25371 S46 R E E G F D R S T S L E S S D
Chimpanzee Pan troglodytes XP_507843 498 53446 S312 R E E G F D R S T S L E S S D
Rhesus Macaque Macaca mulatta XP_001105457 659 70290 S473 R E E G F D R S T S L E S S D
Dog Lupus familis XP_546156 230 24965 S46 E G L G R C A S L E S S D C E
Cat Felis silvestris
Mouse Mus musculus Q9D3F7 229 24852 L46 G L D R C A S L E S S D C E S
Rat Rattus norvegicus Q8VHZ9 229 24867 L46 G L D R C A S L E S S D C E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508688 230 24562 T46 G H S S G L E T S D C E S L D
Chicken Gallus gallus XP_001232608 183 19110
Frog Xenopus laevis Q7SYV9 219 24161 L41 V A Q R C S S L P S S D C E S
Zebra Danio Brachydanio rerio Q7T346 220 23958 S42 Q K L H S S Q S L D S D S D N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VTH4 280 30744 G54 T T G G S S N G S N A T A T S
Honey Bee Apis mellifera XP_625046 157 17786
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787042 182 20622
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.3 34.7 93.9 N.A. 91.8 91.3 N.A. 73.7 43.5 55.1 50 N.A. 20 25 N.A. 25.4
Protein Similarity: 100 46.3 34.9 96.1 N.A. 93.9 93.9 N.A. 81.4 53.4 70.2 65.5 N.A. 39.2 38.7 N.A. 44.4
P-Site Identity: 100 100 100 13.3 N.A. 6.6 6.6 N.A. 20 0 6.6 13.3 N.A. 6.6 0 N.A. 0
P-Site Similarity: 100 100 100 20 N.A. 20 20 N.A. 33.3 0 20 46.6 N.A. 33.3 0 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 16 8 0 0 0 8 0 8 0 0 % A
% Cys: 0 0 0 0 24 8 0 0 0 0 8 0 24 8 0 % C
% Asp: 0 0 16 0 0 24 0 0 0 16 0 31 8 8 31 % D
% Glu: 8 24 24 0 0 0 8 0 16 8 0 31 0 24 8 % E
% Phe: 0 0 0 0 24 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 24 8 8 39 8 0 0 8 0 0 0 0 0 0 0 % G
% His: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 16 16 0 0 8 0 24 16 0 24 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % P
% Gln: 8 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 24 0 0 24 8 0 24 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 8 8 16 24 24 39 16 47 39 8 39 24 31 % S
% Thr: 8 8 0 0 0 0 0 8 24 0 0 8 0 8 0 % T
% Val: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _