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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SDHAF2 All Species: 8.18
Human Site: S27 Identified Species: 16.36
UniProt: Q9NX18 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NX18 NP_060311.1 166 19599 S27 S L L S P L L S V T S F R R F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082359 154 18370 S27 R R F Y R G D S P T D S Q K D
Dog Lupus familis XP_533273 165 19466 S27 H L V S P L L S T P S N R F Y
Cat Felis silvestris
Mouse Mus musculus Q8C6I2 164 19413 T27 L S P L P S V T S F R R F Y R
Rat Rattus norvegicus Q5RJQ7 164 19506 S28 S P L L S V T S F R R F Y R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505276 160 18877 P34 R S Y R G S S P A D S Q K D M
Chicken Gallus gallus XP_423694 154 17901 L28 R G Y S G A S L G D S G K D M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A3KP74 158 18458 V27 R P T V C P V V Y R G Y R G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q4V5I9 163 19175 S29 S M S N M K D S P P P P P P L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9NA72 119 13928
Sea Urchin Strong. purpuratus XP_793951 158 18404 A30 S G V L R G S A C L L S H Q P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08230 162 19023 A27 I N S Q T G S A A W S C G R R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 92.7 88.5 N.A. 90.3 90.3 N.A. 80.7 65 N.A. 56 N.A. 40.3 N.A. 32.5 41.5
Protein Similarity: 100 N.A. 92.7 90.9 N.A. 93.3 93.3 N.A. 84.9 74 N.A. 72.8 N.A. 56.6 N.A. 48.7 58.4
P-Site Identity: 100 N.A. 13.3 53.3 N.A. 6.6 33.3 N.A. 6.6 13.3 N.A. 6.6 N.A. 13.3 N.A. 0 6.6
P-Site Similarity: 100 N.A. 26.6 66.6 N.A. 20 40 N.A. 13.3 20 N.A. 20 N.A. 26.6 N.A. 0 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 37.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 62 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 0 17 17 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 9 0 0 0 9 0 0 9 0 0 0 % C
% Asp: 0 0 0 0 0 0 17 0 0 17 9 0 0 17 17 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 9 0 0 0 0 0 9 9 0 17 9 9 9 % F
% Gly: 0 17 0 0 17 25 0 0 9 0 9 9 9 9 9 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 9 0 0 0 0 0 0 17 9 0 % K
% Leu: 9 17 17 25 0 17 17 9 0 9 9 0 0 0 9 % L
% Met: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 17 % M
% Asn: 0 9 0 9 0 0 0 0 0 0 0 9 0 0 0 % N
% Pro: 0 17 9 0 25 9 0 9 17 17 9 9 9 9 9 % P
% Gln: 0 0 0 9 0 0 0 0 0 0 0 9 9 9 0 % Q
% Arg: 34 9 0 9 17 0 0 0 0 17 17 9 25 25 17 % R
% Ser: 34 17 17 25 9 17 34 42 9 0 42 17 0 0 0 % S
% Thr: 0 0 9 0 9 0 9 9 9 17 0 0 0 0 0 % T
% Val: 0 0 17 9 0 9 17 9 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 0 0 17 9 0 0 0 0 9 0 0 9 9 9 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _