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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SDHAF2 All Species: 10.3
Human Site: Y105 Identified Species: 20.61
UniProt: Q9NX18 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NX18 NP_060311.1 166 19599 Y105 T E K Q L N L Y D R L I N E P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082359 154 18370 W109 N D W D I Y Y W A T E A K P A
Dog Lupus familis XP_533273 165 19466 Y104 T E K Q L N L Y D R L I N E P
Cat Felis silvestris
Mouse Mus musculus Q8C6I2 164 19413 N112 R L I N E P S N D W D I Y Y W
Rat Rattus norvegicus Q5RJQ7 164 19506 N112 R L I N E P S N D W D I Y Y W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505276 160 18877 W115 N D W D I Y Y W A T E A K P A
Chicken Gallus gallus XP_423694 154 17901 W109 N D W D I Y Y W A T E A K P T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A3KP74 158 18458 N107 R L I N E P S N D W D I Y Y W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q4V5I9 163 19175 Y108 S A E Q T A Q Y D Q L I N G V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9NA72 119 13928 E81 L I N G E H M E W D L F Y Y L
Sea Urchin Strong. purpuratus XP_793951 158 18404 F111 P D N D W D L F Y W V V Q H K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08230 162 19023 Y104 N E E E L E E Y D S L L N E L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 92.7 88.5 N.A. 90.3 90.3 N.A. 80.7 65 N.A. 56 N.A. 40.3 N.A. 32.5 41.5
Protein Similarity: 100 N.A. 92.7 90.9 N.A. 93.3 93.3 N.A. 84.9 74 N.A. 72.8 N.A. 56.6 N.A. 48.7 58.4
P-Site Identity: 100 N.A. 0 100 N.A. 13.3 13.3 N.A. 0 0 N.A. 13.3 N.A. 40 N.A. 6.6 6.6
P-Site Similarity: 100 N.A. 20 100 N.A. 13.3 13.3 N.A. 20 20 N.A. 13.3 N.A. 60 N.A. 20 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 37.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 62 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 9 0 0 25 0 0 25 0 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 34 0 34 0 9 0 0 59 9 25 0 0 0 0 % D
% Glu: 0 25 17 9 34 9 9 9 0 0 25 0 0 25 0 % E
% Phe: 0 0 0 0 0 0 0 9 0 0 0 9 0 0 0 % F
% Gly: 0 0 0 9 0 0 0 0 0 0 0 0 0 9 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 9 25 0 25 0 0 0 0 0 0 50 0 0 0 % I
% Lys: 0 0 17 0 0 0 0 0 0 0 0 0 25 0 9 % K
% Leu: 9 25 0 0 25 0 25 0 0 0 42 9 0 0 17 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 34 0 17 25 0 17 0 25 0 0 0 0 34 0 0 % N
% Pro: 9 0 0 0 0 25 0 0 0 0 0 0 0 25 17 % P
% Gln: 0 0 0 25 0 0 9 0 0 9 0 0 9 0 0 % Q
% Arg: 25 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % R
% Ser: 9 0 0 0 0 0 25 0 0 9 0 0 0 0 0 % S
% Thr: 17 0 0 0 9 0 0 0 0 25 0 0 0 0 9 % T
% Val: 0 0 0 0 0 0 0 0 0 0 9 9 0 0 9 % V
% Trp: 0 0 25 0 9 0 0 25 9 34 0 0 0 0 25 % W
% Tyr: 0 0 0 0 0 25 25 34 9 0 0 0 34 34 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _