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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NHP2 All Species: 18.18
Human Site: S19 Identified Species: 30.77
UniProt: Q9NX24 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NX24 NP_060308.1 153 17201 S19 E A Q A E A C S G E R T Y Q E
Chimpanzee Pan troglodytes XP_001145824 153 17300 S19 E A Q A E V C S G E R T Y Q E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531874 153 17217 L19 E A Q A E A C L G E R T Y H E
Cat Felis silvestris
Mouse Mus musculus Q9CRB2 153 17229 S19 E A Q A E G C S E E R T Y K E
Rat Rattus norvegicus NP_001099249 121 13634 S11 I K V V P E E S E A Q L Y K C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515885 99 11028
Chicken Gallus gallus
Frog Xenopus laevis Q6NTV9 149 16756 S19 V P E T P S K S Y D E L L S Y
Zebra Danio Brachydanio rerio Q6PBV6 150 16670 T17 G E E E T G G T E K S Y Q E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3U2 160 17705 S19 A D E S V V A S G D V T I K E
Honey Bee Apis mellifera XP_625159 150 17100 I30 K L K Y T N S I A K P M A S K
Nematode Worm Caenorhab. elegans Q9XXD4 163 18072 N19 E S T V S E A N G D A T A P T
Sea Urchin Strong. purpuratus XP_782391 152 16789 T18 D H A E E A E T Q E L S Y D E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LEY9 156 16930 T21 E K K K Y A I T L A P I A K P
Baker's Yeast Sacchar. cerevisiae P32495 156 17103 A35 L P F A K P L A S K K L N K K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.1 N.A. 94.7 N.A. 89.5 73.8 N.A. 59.4 N.A. 71.2 71.2 N.A. 41.8 47.7 43.5 58.1
Protein Similarity: 100 95.4 N.A. 96.7 N.A. 94.1 76.4 N.A. 63.4 N.A. 86.2 86.2 N.A. 65 70.5 63.7 75.8
P-Site Identity: 100 93.3 N.A. 86.6 N.A. 80 13.3 N.A. 0 N.A. 6.6 0 N.A. 26.6 0 20 33.3
P-Site Similarity: 100 93.3 N.A. 86.6 N.A. 86.6 26.6 N.A. 0 N.A. 26.6 26.6 N.A. 53.3 26.6 40 53.3
Percent
Protein Identity: N.A. N.A. N.A. 38.4 42.9 N.A.
Protein Similarity: N.A. N.A. N.A. 64.7 64.7 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 29 8 36 0 29 15 8 8 15 8 0 22 0 0 % A
% Cys: 0 0 0 0 0 0 29 0 0 0 0 0 0 0 8 % C
% Asp: 8 8 0 0 0 0 0 0 0 22 0 0 0 8 0 % D
% Glu: 43 8 22 15 36 15 15 0 22 36 8 0 0 8 43 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 15 8 0 36 0 0 0 0 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 8 0 0 0 0 0 8 8 0 0 0 8 8 0 0 % I
% Lys: 8 15 15 8 8 0 8 0 0 22 8 0 0 36 15 % K
% Leu: 8 8 0 0 0 0 8 8 8 0 8 22 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 8 0 0 0 0 8 0 0 % N
% Pro: 0 15 0 0 15 8 0 0 0 0 15 0 0 8 8 % P
% Gln: 0 0 29 0 0 0 0 0 8 0 8 0 8 15 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 29 0 0 0 0 % R
% Ser: 0 8 0 8 8 8 8 43 8 0 8 8 0 15 0 % S
% Thr: 0 0 8 8 15 0 0 22 0 0 0 43 0 0 8 % T
% Val: 8 0 8 15 8 15 0 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 8 0 0 0 8 0 0 8 43 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _