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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NHP2 All Species: 23.64
Human Site: S40 Identified Species: 40
UniProt: Q9NX24 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NX24 NP_060308.1 153 17201 S40 P I A Q P L A S R R L T R K L
Chimpanzee Pan troglodytes XP_001145824 153 17300 S40 P I A Q L L A S H R P K R K L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531874 153 17217 S40 P I A Q P L A S R R L T R K L
Cat Felis silvestris
Mouse Mus musculus Q9CRB2 153 17229 S40 P I A Q P L A S R R L T R K L
Rat Rattus norvegicus NP_001099249 121 13634 G31 K Q K Q I R R G V K E V Q K F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515885 99 11028 G9 K Q K Q I R R G V K E V Q K F
Chicken Gallus gallus
Frog Xenopus laevis Q6NTV9 149 16756 T40 P L A G R K L T K K L Y K C V
Zebra Danio Brachydanio rerio Q6PBV6 150 16670 S37 P I A N P L A S R K L S K K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3U2 160 17705 G46 A I A K P M A G K K L A K K C
Honey Bee Apis mellifera XP_625159 150 17100 H53 C I K K A S K H K S Y L R N G
Nematode Worm Caenorhab. elegans Q9XXD4 163 18072 N48 P I A Q P L A N R K L A K K V
Sea Urchin Strong. purpuratus XP_782391 152 16789 S39 P I A N P L A S R K L T K K L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LEY9 156 16930 G47 K L I Q K A A G K K C L K R G
Baker's Yeast Sacchar. cerevisiae P32495 156 17103 V56 K A S K A K N V K R G V K E V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.1 N.A. 94.7 N.A. 89.5 73.8 N.A. 59.4 N.A. 71.2 71.2 N.A. 41.8 47.7 43.5 58.1
Protein Similarity: 100 95.4 N.A. 96.7 N.A. 94.1 76.4 N.A. 63.4 N.A. 86.2 86.2 N.A. 65 70.5 63.7 75.8
P-Site Identity: 100 73.3 N.A. 100 N.A. 100 13.3 N.A. 13.3 N.A. 20 73.3 N.A. 40 13.3 66.6 80
P-Site Similarity: 100 73.3 N.A. 100 N.A. 100 26.6 N.A. 26.6 N.A. 60 93.3 N.A. 73.3 26.6 93.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. 38.4 42.9 N.A.
Protein Similarity: N.A. N.A. N.A. 64.7 64.7 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 65 0 15 8 65 0 0 0 0 15 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 8 0 0 8 8 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 15 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % F
% Gly: 0 0 0 8 0 0 0 29 0 0 8 0 0 0 15 % G
% His: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % H
% Ile: 0 65 8 0 15 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 29 0 22 22 8 15 8 0 36 58 0 8 50 72 0 % K
% Leu: 0 15 0 0 8 50 8 0 0 0 58 15 0 0 43 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 15 0 0 8 8 0 0 0 0 0 8 0 % N
% Pro: 58 0 0 0 50 0 0 0 0 0 8 0 0 0 0 % P
% Gln: 0 15 0 58 0 0 0 0 0 0 0 0 15 0 0 % Q
% Arg: 0 0 0 0 8 15 15 0 43 36 0 0 36 8 0 % R
% Ser: 0 0 8 0 0 8 0 43 0 8 0 8 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 8 0 0 0 29 0 0 0 % T
% Val: 0 0 0 0 0 0 0 8 15 0 0 22 0 0 22 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _