Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NHP2 All Species: 19.39
Human Site: T23 Identified Species: 32.82
UniProt: Q9NX24 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NX24 NP_060308.1 153 17201 T23 E A C S G E R T Y Q E L L V N
Chimpanzee Pan troglodytes XP_001145824 153 17300 T23 E V C S G E R T Y Q E L L V N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531874 153 17217 T23 E A C L G E R T Y H E L L V N
Cat Felis silvestris
Mouse Mus musculus Q9CRB2 153 17229 T23 E G C S E E R T Y K E L L V N
Rat Rattus norvegicus NP_001099249 121 13634 L15 P E E S E A Q L Y K C I K K A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515885 99 11028
Chicken Gallus gallus
Frog Xenopus laevis Q6NTV9 149 16756 L23 P S K S Y D E L L S Y L N P V
Zebra Danio Brachydanio rerio Q6PBV6 150 16670 Y21 T G G T E K S Y Q E L I A N I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3U2 160 17705 T23 V V A S G D V T I K E E E S Y
Honey Bee Apis mellifera XP_625159 150 17100 M34 T N S I A K P M A S K K L T K
Nematode Worm Caenorhab. elegans Q9XXD4 163 18072 T23 S E A N G D A T A P T T E K D
Sea Urchin Strong. purpuratus XP_782391 152 16789 S22 E A E T Q E L S Y D E L V T R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LEY9 156 16930 I25 Y A I T L A P I A K P L A G K
Baker's Yeast Sacchar. cerevisiae P32495 156 17103 L39 K P L A S K K L N K K V L K T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.1 N.A. 94.7 N.A. 89.5 73.8 N.A. 59.4 N.A. 71.2 71.2 N.A. 41.8 47.7 43.5 58.1
Protein Similarity: 100 95.4 N.A. 96.7 N.A. 94.1 76.4 N.A. 63.4 N.A. 86.2 86.2 N.A. 65 70.5 63.7 75.8
P-Site Identity: 100 93.3 N.A. 86.6 N.A. 80 13.3 N.A. 0 N.A. 13.3 0 N.A. 26.6 6.6 13.3 40
P-Site Similarity: 100 93.3 N.A. 86.6 N.A. 86.6 33.3 N.A. 0 N.A. 26.6 26.6 N.A. 40 20 33.3 60
Percent
Protein Identity: N.A. N.A. N.A. 38.4 42.9 N.A.
Protein Similarity: N.A. N.A. N.A. 64.7 64.7 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 29 15 8 8 15 8 0 22 0 0 0 15 0 8 % A
% Cys: 0 0 29 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 22 0 0 0 8 0 0 0 0 8 % D
% Glu: 36 15 15 0 22 36 8 0 0 8 43 8 15 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 15 8 0 36 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 8 8 0 0 0 8 8 0 0 15 0 0 8 % I
% Lys: 8 0 8 0 0 22 8 0 0 36 15 8 8 22 15 % K
% Leu: 0 0 8 8 8 0 8 22 8 0 8 50 43 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 8 0 0 0 0 8 0 0 0 8 8 29 % N
% Pro: 15 8 0 0 0 0 15 0 0 8 8 0 0 8 0 % P
% Gln: 0 0 0 0 8 0 8 0 8 15 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 29 0 0 0 0 0 0 0 8 % R
% Ser: 8 8 8 43 8 0 8 8 0 15 0 0 0 8 0 % S
% Thr: 15 0 0 22 0 0 0 43 0 0 8 8 0 15 8 % T
% Val: 8 15 0 0 0 0 8 0 0 0 0 8 8 29 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 8 0 0 8 43 0 8 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _