Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NHP2 All Species: 43.94
Human Site: Y105 Identified Species: 74.36
UniProt: Q9NX24 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NX24 NP_060308.1 153 17201 Y105 C E D R N L P Y V Y I P S K T
Chimpanzee Pan troglodytes XP_001145824 153 17300 Y105 C E D R N L P Y V Y I P S K T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531874 153 17217 Y105 C E D R N L P Y V Y I P S K T
Cat Felis silvestris
Mouse Mus musculus Q9CRB2 153 17229 Y105 C E D Q N L P Y V Y I P S K T
Rat Rattus norvegicus NP_001099249 121 13634 V74 E D Q N L P Y V Y I P S K T D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515885 99 11028 A52 E D R S L P Y A Y V P S K T D
Chicken Gallus gallus
Frog Xenopus laevis Q6NTV9 149 16756 Y101 C E D R G I P Y S Y V P S K S
Zebra Danio Brachydanio rerio Q6PBV6 150 16670 Y102 C E D R S L P Y A Y V P S K V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3U2 160 17705 Y112 C E E K G I P Y T Y T P S R A
Honey Bee Apis mellifera XP_625159 150 17100 Y102 C E D K N I P Y C Y T P S R Q
Nematode Worm Caenorhab. elegans Q9XXD4 163 18072 Y114 C E E K E I P Y V Y I P S R E
Sea Urchin Strong. purpuratus XP_782391 152 16789 Y104 C E D L D L P Y A Y V P S K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LEY9 156 16930 Y96 C E E A G V P Y V Y V P S K E
Baker's Yeast Sacchar. cerevisiae P32495 156 17103 Y101 C E D H S V P Y I F I P S K Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.1 N.A. 94.7 N.A. 89.5 73.8 N.A. 59.4 N.A. 71.2 71.2 N.A. 41.8 47.7 43.5 58.1
Protein Similarity: 100 95.4 N.A. 96.7 N.A. 94.1 76.4 N.A. 63.4 N.A. 86.2 86.2 N.A. 65 70.5 63.7 75.8
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 0 N.A. 0 N.A. 66.6 73.3 N.A. 46.6 60 60 66.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 6.6 N.A. 6.6 N.A. 86.6 86.6 N.A. 73.3 80 86.6 86.6
Percent
Protein Identity: N.A. N.A. N.A. 38.4 42.9 N.A.
Protein Similarity: N.A. N.A. N.A. 64.7 64.7 N.A.
P-Site Identity: N.A. N.A. N.A. 60 60 N.A.
P-Site Similarity: N.A. N.A. N.A. 80 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 8 15 0 0 0 0 0 8 % A
% Cys: 86 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 15 65 0 8 0 0 0 0 0 0 0 0 0 15 % D
% Glu: 15 86 22 0 8 0 0 0 0 0 0 0 0 0 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 22 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 29 0 0 8 8 43 0 0 0 0 % I
% Lys: 0 0 0 22 0 0 0 0 0 0 0 0 15 65 0 % K
% Leu: 0 0 0 8 15 43 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 36 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 15 86 0 0 0 15 86 0 0 0 % P
% Gln: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 15 % Q
% Arg: 0 0 8 36 0 0 0 0 0 0 0 0 0 22 0 % R
% Ser: 0 0 0 8 15 0 0 0 8 0 0 15 86 0 15 % S
% Thr: 0 0 0 0 0 0 0 0 8 0 15 0 0 15 29 % T
% Val: 0 0 0 0 0 15 0 8 43 8 29 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 15 86 15 79 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _