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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C9orf6
All Species:
36.67
Human Site:
S138
Identified Species:
67.22
UniProt:
Q9NX38
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX38
NP_060302.1
181
20378
S138
S
I
L
Q
E
K
P
S
T
E
G
Y
I
A
V
Chimpanzee
Pan troglodytes
XP_520174
257
28858
S214
S
I
L
Q
E
K
P
S
T
E
G
Y
I
A
V
Rhesus Macaque
Macaca mulatta
XP_001108371
180
20289
S138
S
I
L
Q
E
K
P
S
T
E
G
Y
I
A
V
Dog
Lupus familis
XP_532026
181
20176
S138
S
I
L
Q
E
K
P
S
T
E
G
Y
I
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q80ZQ9
193
21578
S150
S
L
L
Q
E
K
P
S
T
E
G
Y
I
A
V
Rat
Rattus norvegicus
XP_002726576
193
21491
S150
S
L
L
Q
E
K
P
S
T
E
G
Y
I
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513853
179
20086
A135
S
I
L
Q
E
K
P
A
T
E
G
Y
I
A
V
Chicken
Gallus gallus
Q5ZHW7
173
19180
S131
A
L
L
Q
E
K
P
S
T
E
G
Y
I
A
V
Frog
Xenopus laevis
Q6GR35
183
20770
S136
G
L
L
K
E
K
P
S
T
E
G
Y
I
A
V
Zebra Danio
Brachydanio rerio
Q1LU93
177
20485
S135
D
L
L
M
E
K
P
S
T
E
G
Y
I
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFR1
214
23813
E156
K
L
L
E
Q
L
P
E
G
A
G
Y
F
A
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34452
157
17176
T115
M
N
D
R
L
K
T
T
P
D
F
I
R
T
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002300690
205
22985
E163
D
R
L
I
K
Q
P
E
L
L
N
S
S
A
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.1
99.4
96.1
N.A.
81.8
83.9
N.A.
77.3
71.8
73.7
68.5
N.A.
34.5
N.A.
25.4
N.A.
Protein Similarity:
100
63
99.4
97.2
N.A.
86.5
88
N.A.
87.8
83.9
85.7
82.8
N.A.
49
N.A.
44.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
86.6
80
80
N.A.
33.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
86.6
N.A.
60
N.A.
26.6
N.A.
Percent
Protein Identity:
26.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
44.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
8
0
8
0
0
0
93
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
8
0
0
0
0
0
0
8
0
0
0
0
8
% D
% Glu:
0
0
0
8
77
0
0
16
0
77
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
8
0
85
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
39
0
8
0
0
0
0
0
0
0
8
77
0
8
% I
% Lys:
8
0
0
8
8
85
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
47
93
0
8
8
0
0
8
8
0
0
0
0
0
% L
% Met:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
93
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
62
8
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
8
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
54
0
0
0
0
0
0
70
0
0
0
8
8
0
0
% S
% Thr:
0
0
0
0
0
0
8
8
77
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
77
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
85
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _