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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C9orf6
All Species:
44.24
Human Site:
Y166
Identified Species:
81.11
UniProt:
Q9NX38
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX38
NP_060302.1
181
20378
Y166
G
L
L
T
Q
K
Q
Y
E
E
V
M
V
K
R
Chimpanzee
Pan troglodytes
XP_520174
257
28858
Y242
G
L
L
T
Q
K
Q
Y
E
E
V
M
V
K
R
Rhesus Macaque
Macaca mulatta
XP_001108371
180
20289
Y166
G
L
L
T
Q
K
Q
Y
E
E
V
M
V
K
R
Dog
Lupus familis
XP_532026
181
20176
Y166
G
L
L
T
Q
K
Q
Y
E
E
V
V
V
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80ZQ9
193
21578
Y178
G
L
L
T
Q
Q
Q
Y
E
E
V
V
V
K
R
Rat
Rattus norvegicus
XP_002726576
193
21491
Y178
G
L
L
T
Q
Q
Q
Y
E
E
V
L
V
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513853
179
20086
Y163
G
L
L
S
Q
K
E
Y
E
E
I
V
V
K
R
Chicken
Gallus gallus
Q5ZHW7
173
19180
Y159
G
L
L
T
P
E
E
Y
K
E
V
L
L
K
R
Frog
Xenopus laevis
Q6GR35
183
20770
Y164
G
L
L
S
Q
R
E
Y
E
E
I
V
Q
S
R
Zebra Danio
Brachydanio rerio
Q1LU93
177
20485
Y163
G
L
L
T
R
E
Q
Y
E
E
I
L
T
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFR1
214
23813
Y184
S
L
L
T
Q
E
Q
Y
E
E
R
L
K
S
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34452
157
17176
G143
A
G
V
R
E
T
E
G
M
G
D
D
L
P
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002300690
205
22985
S191
D
W
L
K
V
K
A
S
L
L
G
L
E
E
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.1
99.4
96.1
N.A.
81.8
83.9
N.A.
77.3
71.8
73.7
68.5
N.A.
34.5
N.A.
25.4
N.A.
Protein Similarity:
100
63
99.4
97.2
N.A.
86.5
88
N.A.
87.8
83.9
85.7
82.8
N.A.
49
N.A.
44.2
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
73.3
60
53.3
66.6
N.A.
53.3
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
86.6
93.3
N.A.
73.3
N.A.
26.6
N.A.
Percent
Protein Identity:
26.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
44.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% D
% Glu:
0
0
0
0
8
24
31
0
77
85
0
0
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
77
8
0
0
0
0
0
8
0
8
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
24
0
0
0
0
% I
% Lys:
0
0
0
8
0
47
0
0
8
0
0
0
8
70
8
% K
% Leu:
0
85
93
0
0
0
0
0
8
8
0
39
16
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
24
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
8
% P
% Gln:
0
0
0
0
70
16
62
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
8
8
8
0
0
0
0
8
0
0
0
77
% R
% Ser:
8
0
0
16
0
0
0
8
0
0
0
0
0
16
0
% S
% Thr:
0
0
0
70
0
8
0
0
0
0
0
0
8
0
0
% T
% Val:
0
0
8
0
8
0
0
0
0
0
54
31
54
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _