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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HYPK
All Species:
6.36
Human Site:
S70
Identified Species:
10.77
UniProt:
Q9NX55
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX55
NP_057484.3
175
19332
S70
L
E
L
E
T
E
T
S
G
P
E
R
P
P
E
Chimpanzee
Pan troglodytes
XP_001160408
175
19359
S70
L
E
L
E
T
E
T
S
G
P
E
R
P
P
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544652
165
18079
P62
L
E
T
E
T
S
G
P
E
R
P
P
E
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR41
129
14661
R28
T
E
T
S
G
P
E
R
P
P
E
K
P
R
K
Rat
Rattus norvegicus
XP_230510
151
17054
R50
T
E
T
S
G
P
E
R
P
P
E
K
P
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233640
74
8234
Frog
Xenopus laevis
Q6IP73
213
23187
K98
R
V
T
I
R
K
S
K
N
I
L
F
V
I
T
Zebra Danio
Brachydanio rerio
Q8JIU7
215
23381
K100
R
V
T
I
R
K
S
K
N
I
L
F
V
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650329
124
14003
K23
D
E
Q
D
K
K
Q
K
K
S
D
V
K
R
H
Honey Bee
Apis mellifera
XP_624932
147
16724
S46
D
E
V
Q
Q
E
K
S
Q
K
K
T
A
K
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785775
113
12400
A11
D
E
V
E
K
D
A
A
N
A
A
P
K
A
K
Poplar Tree
Populus trichocarpa
XP_002311382
111
12171
D10
G
G
D
G
E
G
I
D
R
V
V
D
S
K
D
Maize
Zea mays
NP_001148118
117
12494
E16
G
A
G
A
A
E
G
E
G
A
V
D
S
K
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94JX9
217
23694
K100
R
V
T
I
K
R
T
K
N
V
L
F
F
I
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
77.1
N.A.
73.1
77.1
N.A.
N.A.
35.4
21.6
22.3
N.A.
37.7
45.7
N.A.
36.5
Protein Similarity:
100
99.4
N.A.
79.4
N.A.
73.7
80
N.A.
N.A.
36
41.3
40.4
N.A.
55.4
60
N.A.
48.5
P-Site Identity:
100
100
N.A.
26.6
N.A.
26.6
26.6
N.A.
N.A.
0
0
0
N.A.
6.6
20
N.A.
13.3
P-Site Similarity:
100
100
N.A.
26.6
N.A.
40
40
N.A.
N.A.
0
13.3
13.3
N.A.
26.6
40
N.A.
40
Percent
Protein Identity:
24.5
29.7
N.A.
22.5
N.A.
N.A.
Protein Similarity:
42.8
47.4
N.A.
38.7
N.A.
N.A.
P-Site Identity:
0
13.3
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
6.6
20
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
8
0
8
8
0
15
8
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
22
0
8
8
0
8
0
8
0
0
8
15
0
0
15
% D
% Glu:
0
58
0
29
8
29
15
8
8
0
29
0
8
0
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
22
8
0
0
% F
% Gly:
15
8
8
8
15
8
15
0
22
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
22
0
0
8
0
0
15
0
0
0
22
0
% I
% Lys:
0
0
0
0
22
22
8
29
8
8
8
15
15
29
22
% K
% Leu:
22
0
15
0
0
0
0
0
0
0
22
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
29
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
15
0
8
15
29
8
15
29
15
8
% P
% Gln:
0
0
8
8
8
0
8
0
8
0
0
0
0
0
0
% Q
% Arg:
22
0
0
0
15
8
0
15
8
8
0
15
0
22
0
% R
% Ser:
0
0
0
15
0
8
15
22
0
8
0
0
15
0
8
% S
% Thr:
15
0
43
0
22
0
22
0
0
0
0
8
0
0
15
% T
% Val:
0
22
15
0
0
0
0
0
0
15
15
8
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _