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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HYPK
All Species:
4.55
Human Site:
Y95
Identified Species:
7.69
UniProt:
Q9NX55
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX55
NP_057484.3
175
19332
Y95
D
L
E
R
V
T
D
Y
A
E
E
K
E
I
Q
Chimpanzee
Pan troglodytes
XP_001160408
175
19359
Y95
D
L
E
R
V
T
D
Y
A
E
E
K
E
I
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544652
165
18079
E87
E
R
V
T
D
Y
A
E
E
K
E
I
Q
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR41
129
14661
K53
V
T
D
Y
A
E
E
K
E
I
Q
S
S
N
L
Rat
Rattus norvegicus
XP_230510
151
17054
K75
V
T
D
Y
A
E
E
K
E
I
Q
S
S
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233640
74
8234
Frog
Xenopus laevis
Q6IP73
213
23187
E123
D
T
Y
I
V
F
G
E
A
K
I
E
D
L
S
Zebra Danio
Brachydanio rerio
Q8JIU7
215
23381
E125
D
T
Y
I
V
F
G
E
A
K
I
E
D
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650329
124
14003
E48
T
D
Y
A
E
E
K
E
I
S
A
D
N
I
S
Honey Bee
Apis mellifera
XP_624932
147
16724
E71
T
D
Y
A
E
E
K
E
I
S
S
S
D
G
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785775
113
12400
E36
K
V
T
D
Y
A
E
E
N
V
I
S
G
Q
D
Poplar Tree
Populus trichocarpa
XP_002311382
111
12171
R35
L
T
D
R
V
E
D
R
Q
L
D
S
T
R
V
Maize
Zea mays
NP_001148118
117
12494
R41
L
T
D
H
V
E
D
R
Q
L
D
S
S
R
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94JX9
217
23694
E125
E
T
Y
V
I
F
G
E
A
K
I
E
D
L
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
77.1
N.A.
73.1
77.1
N.A.
N.A.
35.4
21.6
22.3
N.A.
37.7
45.7
N.A.
36.5
Protein Similarity:
100
99.4
N.A.
79.4
N.A.
73.7
80
N.A.
N.A.
36
41.3
40.4
N.A.
55.4
60
N.A.
48.5
P-Site Identity:
100
100
N.A.
6.6
N.A.
0
0
N.A.
N.A.
0
20
20
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
N.A.
26.6
N.A.
20
20
N.A.
N.A.
0
46.6
46.6
N.A.
6.6
6.6
N.A.
13.3
Percent
Protein Identity:
24.5
29.7
N.A.
22.5
N.A.
N.A.
Protein Similarity:
42.8
47.4
N.A.
38.7
N.A.
N.A.
P-Site Identity:
20
13.3
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
33.3
26.6
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
15
8
8
0
36
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
29
15
29
8
8
0
29
0
0
0
15
8
29
0
8
% D
% Glu:
15
0
15
0
15
43
22
50
22
15
22
22
15
0
0
% E
% Phe:
0
0
0
0
0
22
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
22
0
0
0
0
0
8
8
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
15
8
0
0
0
15
15
29
8
0
22
0
% I
% Lys:
8
0
0
0
0
0
15
15
0
29
0
15
0
0
0
% K
% Leu:
15
15
0
0
0
0
0
0
0
15
0
0
0
22
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
8
15
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
15
0
15
0
8
8
15
% Q
% Arg:
0
8
0
22
0
0
0
15
0
0
0
0
0
15
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
15
8
43
22
8
36
% S
% Thr:
15
50
8
8
0
15
0
0
0
0
0
0
8
0
0
% T
% Val:
15
8
8
8
43
0
0
0
0
8
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
36
15
8
8
0
15
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _