Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LYAR All Species: 13.33
Human Site: S244 Identified Species: 20.95
UniProt: Q9NX58 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NX58 NP_001139197.1 379 43615 S244 E V P E A N G S A G K R S K K
Chimpanzee Pan troglodytes XP_001153728 379 43666 S244 E V P E A D G S A G K R S K K
Rhesus Macaque Macaca mulatta XP_001096675 379 43478 S244 E V P E A N G S A G K R S K K
Dog Lupus familis XP_536242 380 42964 S237 A G E E A P A S A G K K S Q S
Cat Felis silvestris
Mouse Mus musculus Q08288 388 43717 A247 G P P E K K K A Q G G Q A S E
Rat Rattus norvegicus Q6AYK5 386 43662 A234 E A G G E D A A E A N G A P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511111 391 45222 A241 E T A D I N N A E K K K K R K
Chicken Gallus gallus XP_420792 364 42082 K216 Q P A S S E T K K N K K S K K
Frog Xenopus laevis NP_001086609 360 41600 T204 L V E E Q M E T V E K N K S K
Zebra Danio Brachydanio rerio NP_956973 320 37238 R199 K H T Q K Q K R K R E Q N E Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610573 281 32090 E169 A K A E K I A E I Q Q K Q K A
Honey Bee Apis mellifera XP_623803 246 28455 V134 G H K I P S A V V D S V W N K
Nematode Worm Caenorhab. elegans Q09464 253 28497 K141 A I A A E A D K M R E E A I R
Sea Urchin Strong. purpuratus XP_780603 1141 125640 N291 K K K S N D R N D S K P A E N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P37263 153 17720 D41 D C S K T F E D G V S Y K N H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.8 97.3 76.8 N.A. 72.6 74.8 N.A. 62.9 55.6 53.2 43.7 N.A. 27.1 26.9 29.8 20.2
Protein Similarity: 100 98.9 98.6 85.5 N.A. 83.5 86.5 N.A. 76.2 71.7 69.9 64.3 N.A. 46.9 40.1 44.8 28.1
P-Site Identity: 100 93.3 100 46.6 N.A. 20 6.6 N.A. 26.6 26.6 26.6 0 N.A. 13.3 6.6 0 6.6
P-Site Similarity: 100 100 100 60 N.A. 46.6 33.3 N.A. 53.3 46.6 33.3 46.6 N.A. 26.6 13.3 26.6 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 27.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 7 27 7 27 7 27 20 27 7 0 0 27 0 7 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 7 0 20 7 7 7 7 0 0 0 0 0 % D
% Glu: 34 0 14 47 14 7 14 7 14 7 14 7 0 14 14 % E
% Phe: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % F
% Gly: 14 7 7 7 0 0 20 0 7 34 7 7 0 0 0 % G
% His: 0 14 0 0 0 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 0 7 0 7 7 7 0 0 7 0 0 0 0 7 0 % I
% Lys: 14 14 14 7 20 7 14 14 14 7 54 27 20 34 47 % K
% Leu: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 7 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 20 7 7 0 7 7 7 7 14 7 % N
% Pro: 0 14 27 0 7 7 0 0 0 0 0 7 0 7 0 % P
% Gln: 7 0 0 7 7 7 0 0 7 7 7 14 7 7 7 % Q
% Arg: 0 0 0 0 0 0 7 7 0 14 0 20 0 7 7 % R
% Ser: 0 0 7 14 7 7 0 27 0 7 14 0 34 14 7 % S
% Thr: 0 7 7 0 7 0 7 7 0 0 0 0 0 0 0 % T
% Val: 0 27 0 0 0 0 0 7 14 7 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _