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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM161A
All Species:
11.52
Human Site:
S416
Identified Species:
25.33
UniProt:
Q9NX61
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX61
NP_060284.1
479
53602
S416
S
P
D
P
S
S
A
S
A
A
P
I
G
S
G
Chimpanzee
Pan troglodytes
XP_512520
502
56149
S439
S
P
D
P
S
S
A
S
A
A
P
I
G
S
G
Rhesus Macaque
Macaca mulatta
XP_001115682
479
53694
S416
S
P
N
P
S
S
A
S
A
A
S
I
G
F
G
Dog
Lupus familis
XP_541926
526
59380
H463
S
R
T
P
S
S
T
H
D
R
L
G
G
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCA6
480
53996
A417
A
P
S
Q
P
S
E
A
L
I
P
V
D
P
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512011
488
53801
P414
P
S
L
P
A
T
A
P
A
A
G
R
L
S
S
Chicken
Gallus gallus
XP_424528
541
61371
E478
L
P
N
S
A
Y
S
E
S
L
P
A
D
G
K
Frog
Xenopus laevis
Q6GMB1
489
56176
S416
F
S
P
V
V
D
S
S
P
V
Q
S
H
S
P
Zebra Danio
Brachydanio rerio
Q0V947
495
55631
D432
P
G
P
E
D
D
E
D
M
E
D
M
E
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394096
490
56055
Q417
P
E
E
C
P
A
D
Q
L
P
K
F
I
S
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790739
517
58155
T429
N
A
T
N
A
S
A
T
A
M
P
N
S
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
97
79.4
N.A.
82.7
N.A.
N.A.
64.5
43.6
58.6
56.7
N.A.
N.A.
35
N.A.
37.3
Protein Similarity:
100
95
98.1
83.4
N.A.
89.7
N.A.
N.A.
75.1
62.2
75
74.3
N.A.
N.A.
57.1
N.A.
58.2
P-Site Identity:
100
100
80
40
N.A.
20
N.A.
N.A.
33.3
13.3
13.3
0
N.A.
N.A.
6.6
N.A.
26.6
P-Site Similarity:
100
100
86.6
40
N.A.
40
N.A.
N.A.
46.6
40
20
6.6
N.A.
N.A.
20
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
28
10
46
10
46
37
0
10
0
0
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
0
10
19
10
10
10
0
10
0
19
0
19
% D
% Glu:
0
10
10
10
0
0
19
10
0
10
0
0
10
10
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
10
10
37
10
37
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
28
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% K
% Leu:
10
0
10
0
0
0
0
0
19
10
10
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
10
10
0
10
0
0
0
% M
% Asn:
10
0
19
10
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
28
46
19
46
19
0
0
10
10
10
46
0
0
19
19
% P
% Gln:
0
0
0
10
0
0
0
10
0
0
10
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
10
0
10
0
0
0
% R
% Ser:
37
19
10
10
37
55
19
37
10
0
10
10
10
46
10
% S
% Thr:
0
0
19
0
0
10
10
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
10
0
0
0
0
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _