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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IMPAD1 All Species: 22.73
Human Site: S168 Identified Species: 50
UniProt: Q9NX62 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NX62 NP_060283.3 359 38681 S168 P K E V P A E S V T V W I D P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086527 359 38719 S168 P K E V P A E S V T V W I D P
Dog Lupus familis XP_535082 360 38686 S169 P K E V P A E S V T V W I D P
Cat Felis silvestris
Mouse Mus musculus Q80V26 356 38598 S166 P K E V P A E S V T V W I D P
Rat Rattus norvegicus Q9Z1N4 308 33156 N132 Y T E G L L D N V T V L I G I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419214 356 38718 S165 P K E V P A E S V T V W I D P
Frog Xenopus laevis Q6NTW5 351 38099 S156 S K P V S S E S I T I W I D P
Zebra Danio Brachydanio rerio Q2YDR3 341 37413 K151 G K E I P A E K I T V W I D P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VYF2 355 39317 D161 D V T V N A Q D V T V W V D P
Honey Bee Apis mellifera XP_001122543 276 30902 T100 M V H S L L E T F P S I T D E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792363 354 38838 D153 D E K I P V S D I T V W V D P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.8 98 N.A. 91 20.6 N.A. N.A. 81 69.3 60.7 N.A. 40.1 32.3 N.A. 44.5
Protein Similarity: 100 N.A. 99.4 99.4 N.A. 95.8 40.6 N.A. N.A. 90.2 81.3 76.5 N.A. 56.2 48.7 N.A. 64.6
P-Site Identity: 100 N.A. 100 100 N.A. 100 33.3 N.A. N.A. 100 60 73.3 N.A. 53.3 13.3 N.A. 40
P-Site Similarity: 100 N.A. 100 100 N.A. 100 46.6 N.A. N.A. 100 80 86.6 N.A. 66.6 20 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 64 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 19 0 0 0 0 0 10 19 0 0 0 0 0 91 0 % D
% Glu: 0 10 64 0 0 0 73 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 10 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 19 0 0 0 0 28 0 10 10 73 0 10 % I
% Lys: 0 64 10 0 0 0 0 10 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 19 19 0 0 0 0 0 10 0 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 46 0 10 0 64 0 0 0 0 10 0 0 0 0 82 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 0 10 10 10 10 55 0 0 10 0 0 0 0 % S
% Thr: 0 10 10 0 0 0 0 10 0 91 0 0 10 0 0 % T
% Val: 0 19 0 64 0 10 0 0 64 0 82 0 19 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 82 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _