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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IMPAD1 All Species: 22.73
Human Site: S224 Identified Species: 50
UniProt: Q9NX62 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NX62 NP_060283.3 359 38681 S224 W A M V D G G S N V K A R S S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001086527 359 38719 S224 W A M V D G G S N V K A R S S
Dog Lupus familis XP_535082 360 38686 S225 W A M V D G G S N V K A R T S
Cat Felis silvestris
Mouse Mus musculus Q80V26 356 38598 S222 W A M V D G G S N V K A R S S
Rat Rattus norvegicus Q9Z1N4 308 33156 K183 G A F G F Q L K E A P A G K H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419214 356 38718 S221 W A M V D G G S N V K A R S L
Frog Xenopus laevis Q6NTW5 351 38099 A212 W A M V D E G A N I K K R S S
Zebra Danio Brachydanio rerio Q2YDR3 341 37413 S207 W G F V G E G S N V A P R D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VYF2 355 39317 S222 N S M S E Y L S N L H P Q H S
Honey Bee Apis mellifera XP_001122543 276 30902 V151 K G K P I I G V I Y K P F E T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792363 354 38838 L216 G K G H A A H L K E I K H H T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.8 98 N.A. 91 20.6 N.A. N.A. 81 69.3 60.7 N.A. 40.1 32.3 N.A. 44.5
Protein Similarity: 100 N.A. 99.4 99.4 N.A. 95.8 40.6 N.A. N.A. 90.2 81.3 76.5 N.A. 56.2 48.7 N.A. 64.6
P-Site Identity: 100 N.A. 100 93.3 N.A. 100 13.3 N.A. N.A. 93.3 73.3 53.3 N.A. 26.6 13.3 N.A. 0
P-Site Similarity: 100 N.A. 100 100 N.A. 100 13.3 N.A. N.A. 93.3 86.6 53.3 N.A. 53.3 20 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 64 0 0 10 10 0 10 0 10 10 55 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 55 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 10 19 0 0 10 10 0 0 0 10 0 % E
% Phe: 0 0 19 0 10 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 19 19 10 10 10 46 73 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 10 0 0 10 0 0 0 10 0 10 19 10 % H
% Ile: 0 0 0 0 10 10 0 0 10 10 10 0 0 0 0 % I
% Lys: 10 10 10 0 0 0 0 10 10 0 64 19 0 10 0 % K
% Leu: 0 0 0 0 0 0 19 10 0 10 0 0 0 0 10 % L
% Met: 0 0 64 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 73 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 0 0 0 0 0 10 28 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 64 0 0 % R
% Ser: 0 10 0 10 0 0 0 64 0 0 0 0 0 46 64 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 19 % T
% Val: 0 0 0 64 0 0 0 10 0 55 0 0 0 0 0 % V
% Trp: 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _