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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IMPAD1
All Species:
20
Human Site:
S246
Identified Species:
44
UniProt:
Q9NX62
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX62
NP_060283.3
359
38681
S246
I
V
V
S
R
S
H
S
G
M
V
K
Q
V
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086527
359
38719
S246
I
V
V
S
R
S
H
S
G
M
V
R
Q
V
A
Dog
Lupus familis
XP_535082
360
38686
S247
I
I
V
S
R
S
H
S
G
M
V
K
Q
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80V26
356
38598
A244
I
I
V
S
R
S
H
A
G
M
V
K
Q
V
A
Rat
Rattus norvegicus
Q9Z1N4
308
33156
D205
H
S
N
K
L
V
T
D
C
I
A
A
M
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419214
356
38718
A243
I
I
V
S
R
S
H
A
G
K
V
E
Q
V
A
Frog
Xenopus laevis
Q6NTW5
351
38099
S234
F
I
V
S
R
S
H
S
G
E
V
K
E
V
T
Zebra Danio
Brachydanio rerio
Q2YDR3
341
37413
A229
V
I
V
S
R
S
H
A
G
K
V
K
S
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYF2
355
39317
T244
I
T
V
S
R
S
H
T
A
G
A
K
D
L
A
Honey Bee
Apis mellifera
XP_001122543
276
30902
E173
W
S
W
T
N
H
L
E
D
E
R
I
P
I
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792363
354
38838
S238
I
I
V
S
R
S
H
S
G
Q
V
E
E
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.8
98
N.A.
91
20.6
N.A.
N.A.
81
69.3
60.7
N.A.
40.1
32.3
N.A.
44.5
Protein Similarity:
100
N.A.
99.4
99.4
N.A.
95.8
40.6
N.A.
N.A.
90.2
81.3
76.5
N.A.
56.2
48.7
N.A.
64.6
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
86.6
0
N.A.
N.A.
73.3
66.6
53.3
N.A.
53.3
0
N.A.
66.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
6.6
N.A.
N.A.
93.3
80
73.3
N.A.
66.6
13.3
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
28
10
0
19
10
0
0
55
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
10
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
0
19
0
19
19
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
73
10
0
0
0
0
0
% G
% His:
10
0
0
0
0
10
82
0
0
0
0
0
0
0
0
% H
% Ile:
64
55
0
0
0
0
0
0
0
10
0
10
0
10
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
19
0
55
0
0
0
% K
% Leu:
0
0
0
0
10
0
10
0
0
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
37
0
0
10
0
0
% M
% Asn:
0
0
10
0
10
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
46
0
0
% Q
% Arg:
0
0
0
0
82
0
0
0
0
0
10
10
0
0
0
% R
% Ser:
0
19
0
82
0
82
0
46
0
0
0
0
10
0
10
% S
% Thr:
0
10
0
10
0
0
10
10
0
0
0
0
0
0
10
% T
% Val:
10
19
82
0
0
10
0
0
0
0
73
0
0
64
10
% V
% Trp:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _