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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF434 All Species: 11.82
Human Site: Y46 Identified Species: 43.33
UniProt: Q9NX65 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NX65 NP_060280.2 485 54929 Y46 A T G V P W G Y E E T K T L L
Chimpanzee Pan troglodytes A2T736 578 65733 A74 E A L I Q L R A L C H Q W L R
Rhesus Macaque Macaca mulatta XP_001094043 696 78592 Y257 A T G V P W G Y E E T K T L L
Dog Lupus familis XP_535446 852 97433 Y411 P S G V H W G Y E E T K T Y L
Cat Felis silvestris
Mouse Mus musculus B2KFW1 1030 115360 Y320 V S G V H W G Y E E T K T F L
Rat Rattus norvegicus Q4KLI1 562 63347 Q141 L E L D L S G Q Q V P G Q V H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507354 875 99580 F265 V A G V H W S F E E T K T F L
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28 65.8 31.2 N.A. 23.9 30.6 N.A. 33.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 42.7 67.9 39.9 N.A. 31.8 43.9 N.A. 42 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 73.3 N.A. 73.3 6.6 N.A. 60 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 100 80 N.A. 80 20 N.A. 66.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 29 0 0 0 0 0 15 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % C
% Asp: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 15 15 0 0 0 0 0 0 72 72 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 15 0 0 0 0 0 29 0 % F
% Gly: 0 0 72 0 0 0 72 0 0 0 0 15 0 0 0 % G
% His: 0 0 0 0 43 0 0 0 0 0 15 0 0 0 15 % H
% Ile: 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 72 0 0 0 % K
% Leu: 15 0 29 0 15 15 0 0 15 0 0 0 0 43 72 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 15 0 0 0 29 0 0 0 0 0 15 0 0 0 0 % P
% Gln: 0 0 0 0 15 0 0 15 15 0 0 15 15 0 0 % Q
% Arg: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 15 % R
% Ser: 0 29 0 0 0 15 15 0 0 0 0 0 0 0 0 % S
% Thr: 0 29 0 0 0 0 0 0 0 0 72 0 72 0 0 % T
% Val: 29 0 0 72 0 0 0 0 0 15 0 0 0 15 0 % V
% Trp: 0 0 0 0 0 72 0 0 0 0 0 0 15 0 0 % W
% Tyr: 0 0 0 0 0 0 0 58 0 0 0 0 0 15 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _