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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DUS2L All Species: 26.06
Human Site: S295 Identified Species: 44.1
UniProt: Q9NX74 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NX74 NP_060273.1 493 55050 S295 M L R E Q L E S P Q G R L L H
Chimpanzee Pan troglodytes XP_001166638 493 55074 S295 M L R E Q L E S P Q G R L L H
Rhesus Macaque Macaca mulatta XP_001097732 492 55071 S294 M L R E Q L E S P Q G R L L H
Dog Lupus familis XP_546866 560 62189 S362 M L R E Q L E S P Q G R L L H
Cat Felis silvestris
Mouse Mus musculus Q9D7B1 493 55306 S295 M L R E Q L E S P Q G R L L H
Rat Rattus norvegicus Q8K582 438 49691 L267 V R Q H P C P L S Y V R A H L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414079 518 58426 T322 M L R E Q L E T A Q G K K L H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001342694 504 56694 S300 M L R D R V E S P F G K R L H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572950 473 52758 R302 Y C V Q S I L R E L Q E T P R
Honey Bee Apis mellifera XP_393745 457 52069 I286 T K Y C I Q N I L R E Q Q E S
Nematode Worm Caenorhab. elegans NP_493554 436 48980 A265 I R N F L E L A C Q Y D E S Y
Sea Urchin Strong. purpuratus XP_001190481 278 31026 I107 V E K D V S G I D I N M G C P
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001132459 320 35812 K149 L D T T V T C K I R L L N T P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53720 384 42798 Q213 A E I Y E I C Q A N N V S L I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.7 80.1 N.A. 90.2 22.5 N.A. N.A. 67.5 N.A. 60.9 N.A. 44.4 42.5 37.9 38.7
Protein Similarity: 100 99.5 98.5 84.6 N.A. 95.3 39.7 N.A. N.A. 79.7 N.A. 76.9 N.A. 60.4 59.4 56.5 48
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. N.A. 73.3 N.A. 60 N.A. 0 0 6.6 0
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. N.A. 86.6 N.A. 86.6 N.A. 13.3 13.3 26.6 20
Percent
Protein Identity: N.A. 35.5 N.A. N.A. 30.6 N.A.
Protein Similarity: N.A. 46.6 N.A. N.A. 46.6 N.A.
P-Site Identity: N.A. 0 N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. 13.3 N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 8 15 0 0 0 8 0 0 % A
% Cys: 0 8 0 8 0 8 15 0 8 0 0 0 0 8 0 % C
% Asp: 0 8 0 15 0 0 0 0 8 0 0 8 0 0 0 % D
% Glu: 0 15 0 43 8 8 50 0 8 0 8 8 8 8 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 8 0 0 0 50 0 8 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 50 % H
% Ile: 8 0 8 0 8 15 0 15 8 8 0 0 0 0 8 % I
% Lys: 0 8 8 0 0 0 0 8 0 0 0 15 8 0 0 % K
% Leu: 8 50 0 0 8 43 15 8 8 8 8 8 36 58 8 % L
% Met: 50 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 8 0 0 0 8 0 0 8 15 0 8 0 0 % N
% Pro: 0 0 0 0 8 0 8 0 43 0 0 0 0 8 15 % P
% Gln: 0 0 8 8 43 8 0 8 0 50 8 8 8 0 0 % Q
% Arg: 0 15 50 0 8 0 0 8 0 15 0 43 8 0 8 % R
% Ser: 0 0 0 0 8 8 0 43 8 0 0 0 8 8 8 % S
% Thr: 8 0 8 8 0 8 0 8 0 0 0 0 8 8 0 % T
% Val: 15 0 8 0 15 8 0 0 0 0 8 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 8 8 0 0 0 0 0 8 8 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _