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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUS2L
All Species:
20
Human Site:
S484
Identified Species:
33.85
UniProt:
Q9NX74
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX74
NP_060273.1
493
55050
S484
K
P
F
V
A
L
G
S
G
E
E
S
P
L
E
Chimpanzee
Pan troglodytes
XP_001166638
493
55074
S484
K
P
F
V
A
L
G
S
G
E
E
S
P
L
E
Rhesus Macaque
Macaca mulatta
XP_001097732
492
55071
S483
K
P
F
V
A
L
G
S
G
E
E
S
P
L
E
Dog
Lupus familis
XP_546866
560
62189
S551
K
L
F
V
A
L
G
S
G
E
E
S
P
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7B1
493
55306
S484
K
P
F
V
T
L
D
S
S
E
E
N
L
L
E
Rat
Rattus norvegicus
Q8K582
438
49691
G430
R
E
T
A
D
C
P
G
H
D
C
F
L
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414079
518
58426
S508
K
A
S
F
A
E
E
S
S
D
M
N
A
P
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001342694
504
56694
T492
E
E
E
V
T
C
R
T
K
V
V
N
G
V
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572950
473
52758
L465
G
Q
L
E
A
E
V
L
R
D
N
G
S
L
L
Honey Bee
Apis mellifera
XP_393745
457
52069
F449
G
L
I
S
E
K
T
F
D
T
N
S
N
V
P
Nematode Worm
Caenorhab. elegans
NP_493554
436
48980
L428
H
G
M
N
I
R
N
L
L
V
G
N
W
E
E
Sea Urchin
Strong. purpuratus
XP_001190481
278
31026
Q270
R
Y
I
Q
Y
E
N
Q
G
R
R
I
L
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001132459
320
35812
Y312
L
Y
G
E
E
D
Y
Y
N
F
V
V
A
N
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53720
384
42798
K376
G
S
D
T
K
K
Q
K
V
V
P
L
P
T
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
80.1
N.A.
90.2
22.5
N.A.
N.A.
67.5
N.A.
60.9
N.A.
44.4
42.5
37.9
38.7
Protein Similarity:
100
99.5
98.5
84.6
N.A.
95.3
39.7
N.A.
N.A.
79.7
N.A.
76.9
N.A.
60.4
59.4
56.5
48
P-Site Identity:
100
100
100
93.3
N.A.
66.6
0
N.A.
N.A.
20
N.A.
6.6
N.A.
13.3
6.6
6.6
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
73.3
13.3
N.A.
N.A.
40
N.A.
33.3
N.A.
20
13.3
13.3
13.3
Percent
Protein Identity:
N.A.
35.5
N.A.
N.A.
30.6
N.A.
Protein Similarity:
N.A.
46.6
N.A.
N.A.
46.6
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
0
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
43
0
0
0
0
0
0
0
15
0
0
% A
% Cys:
0
0
0
0
0
15
0
0
0
0
8
0
0
0
8
% C
% Asp:
0
0
8
0
8
8
8
0
8
22
0
0
0
0
8
% D
% Glu:
8
15
8
15
15
22
8
0
0
36
36
0
0
15
43
% E
% Phe:
0
0
36
8
0
0
0
8
0
8
0
8
0
0
0
% F
% Gly:
22
8
8
0
0
0
29
8
36
0
8
8
8
0
0
% G
% His:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
15
0
8
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
43
0
0
0
8
15
0
8
8
0
0
0
0
0
8
% K
% Leu:
8
15
8
0
0
36
0
15
8
0
0
8
22
43
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
15
0
8
0
15
29
8
8
0
% N
% Pro:
0
29
0
0
0
0
8
0
0
0
8
0
36
8
15
% P
% Gln:
0
8
0
8
0
0
8
8
0
0
0
0
0
0
0
% Q
% Arg:
15
0
0
0
0
8
8
0
8
8
8
0
0
8
8
% R
% Ser:
0
8
8
8
0
0
0
43
15
0
0
36
8
0
0
% S
% Thr:
0
0
8
8
15
0
8
8
0
8
0
0
0
8
8
% T
% Val:
0
0
0
43
0
0
8
0
8
22
15
8
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
15
0
0
8
0
8
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _